QUESTION & ANSWER
Q: How long does ibuprofen stay in your system?

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A:

It can take up to 24 hours to completely rid your system of ibuprofen, even though its effects generally last about 4 to 6 hours. According to the prescribing information, the ibuprofen half-life is about two hours. In case of an ibuprofen overdose, call 911 or Poison Control at 800-222-1222.

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THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Never ignore professional medical advice in seeking treatment because of something you have read on the site. If you think you may have a medical emergency, immediately call your doctor or dial 911.
  1. Ibuprofen (Oral Route). Mayo Foundation for Medical Education and Research. https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/description/drg-20070602 

    Ibuprofen Prescribing Information. Drugs.com. https://www.drugs.com/pro/ibuprofen.html