Q: How long does Seroquel stay in your system?

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The Seroquel (quetiapine) half-life is about six hours. This means it stays in your system for about 1.5 days. Age, liver disease, and severe kidney disease can prolong the process of clearing Seroquel from the body. Do not stop Seroquel suddenly. Doctors slowly decrease the Seroquel dosage to prevent withdrawal symptoms.

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THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Never ignore professional medical advice in seeking treatment because of something you have read on the site. If you think you may have a medical emergency, immediately call your doctor or dial 911.
  1. Quetiapine. U.S. National Library of Medicine.  
  2. Seroquel Prescribing Information. 

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