If you’re having trouble getting pregnant, you’re not alone. About 12% of women seek services for infertility—defined as not getting pregnant after a year of having sex with no birth control—at some point in their lives. But having infertility problems doesn’t mean you will never get pregnant. You may just need some help. Here are some of the most common treatments. Medicines for Infertility If you are not ovulating (releasing an egg each month), your doctor may suggest medication. The specific drug your doctor recommends depends on the underlying reason for your ovulation problems, such as polycystic ovary syndrome. Many prescription medications can increase your chances of having not just one baby, but twins or multiple births. They include: Bromocriptine (Parlodel), taken by mouth Clomiphene citrate (Clomid), taken by mouth Follicle-stimulating hormone (Follistim, Gonal-F), taken by injection in most cases Human menopausal gonadotropin (Pergonal, Repronex), taken by injection Metformin (Glucophage), taken by mouth Intrauterine Insemination Your doctor may suggest intrauterine insemination (IUI) if your male partner has mild infertility problems or the cause of your infertility is not known. In this treatment, a large amount of healthy sperm is placed into your uterus around the time of ovulation. You may also take medicines to help you ovulate and increase your chance of getting pregnant. Be aware that taking these medicines increases your chance of having twins or multiple births. The success rate for IUI varies, but can be as high as 20%. Assisted Reproductive Technology Assisted reproductive technology (ART) includes all treatments where both sperm and eggs are handled outside of the body. The success rate of ART decreases with age. For example, in women younger than age 35, the success rate is about 40%, while in women ages 44 and older, it is 2%. There are a few different types of ART: In vitro fertilization (IVF). This is the most common type of ART. For this treatment, your eggs are removed and fertilized with sperm in a laboratory. Your doctor places the resulting embryos in your uterus. Zygote intrafallopian transfer (ZIFT). This is similar to IVF except the embryo is placed into the fallopian tube. Gamete intrafallopian transfer (GIFT). In this treatment, both eggs and sperm are transferred into the fallopian tube so that fertilization occurs inside the woman’s body. Intracytoplasmic sperm injection (ICSI). This treatment involves injecting a single sperm into an egg to be fertilized. The embryo is then placed back inside the uterus. ICSI is particularly effective for certain kinds of male infertility because the sperm is manually injected into the egg instead of the sperm fertilizing the egg on its own. ART increases your risk of having twins or multiple births, and IVF may cause a slightly higher risk of birth defects, such as cleft palate and heart problems. Other Fertility Treatment Options Depending on the cause of your fertility problems, you may also want to consider one of the following options: Egg donation. If you do not have healthy eggs or have had your ovaries removed, you can get an egg from a female donor. The egg is fertilized by your partner’s sperm and placed inside your uterus. Sperm donation. This treatment may be helpful if your partner does not produce enough sperm or has a genetic disease that you do not want to pass along. The sperm comes from a donor and can be used with IVF or IUI. Gestational carrier. This may be an option if you have healthy eggs but can’t carry a pregnancy to term. In this case, your egg is fertilized by your partner’s sperm and the embryo is placed inside another woman’s uterus. Surrogacy. There are different types of surrogacy. A surrogate is a woman who becomes pregnant for you using either her own egg or a donor’s egg and your partner’s sperm. It differs from a gestational carrier, which is specifically the parents’ egg and sperm in another uterus. The vast majority of surrogates in the U.S. carry a fetus that is not related to them genetically. Surgery. Some causes of infertility may be treated with surgery including endometriosis, damaged or blocked fallopian tubes, and some male infertility problems. Paying for Treatment Infertility treatments can be expensive. For example, one cycle of IVF can cost as much as $13,000, including medication. Insurance may cover the costs of treatment, but this varies from state to state. Fifteen states have passed laws that require health plans to offer some coverage for these treatments. Check with your health plan to see if it covers any costs of your treatment.