Find a Doctor Find a Doctor
Time to see a specialist? Time to see a specialist?
We found [COUNT] Specialists
who treat [INTEREST]
near [LOCATION]
We found [COUNT] Specialists
who treat [INTEREST]
near [LOCATION]
[TELEHEALTH] offer Telehealth options.
More
Your Guide to Preventing Migraines

This content is created by Healthgrades and brought to you by an advertising sponsor. More

This content is created or selected by the Healthgrades editorial team and is funded by an advertising sponsor. The content is subject to the Healthgrades medical review process for accuracy, balance and objectivity. The content is not edited or otherwise influenced by the advertisers appearing on this page except with the possible suggestion of the broad topic area. For more information, read the Healthgrades advertising policy.

Migraine Sufferers: 5 Reasons It May Be Time to See Your Doctor

Medically Reviewed By William C. Lloyd III, MD, FACS
Female Caucasian doctor comforting patient with head pain
Getty

If you suffer from migraine attacks, you’ve undoubtedly developed some coping strategies. You may have a favorite medication to treat migraine pain, or perhaps you have a tried-and-true preventive medication that you always take. But at some point, you might experience some symptoms or changes in your usual symptoms that warrant a visit to your doctor. And if you have relied on Excedrin Migraine, a popular over-the-counter (OTC) combination medication, you might want to call your doctor to discuss alternatives, since that combination drug may not be available for a while. Consider these five reasons that might inspire you to schedule a visit with your doctor.

1. You’ve been using Excedrin to treat your migraine pain.

Drug manufacturer Novartis announced in January of 2020 that it was voluntarily pulling Excedrin Extra Strength and Excedrin Migraine off the shelf for the foreseeable future. (It also pulled Bufferin, NoDoz, and Gas-X Prevention.) The company noted broken or chipped tablets or even tablets from other products might have gotten mixed in with the drugs. You might accidentally get a product contaminated with an unexpected ingredient that could cause an allergic reaction, or your Excedrin might contain too much of a particular ingredient, raising the possibility of an overdose. Without this treatment option, you may be scrambling for something else. This is a good chance to talk with your doctor about the best alternatives to try.

2. Your headaches are getting worse.

Watch out for increases in the frequency or intensity of your headaches. If your migraines have started getting worse, or you’re having them more often, that’s a cue to call your doctor. If your migraines wake you up at night, that could be another sign. When your headaches begin to disrupt your activities of daily living–or make a bigger impact than usual–that’s another cue.

A good way to keep track of possible changes is to keep a headache diary. You can describe the length and intensity of your headaches after they occur, along with the time of day and what you were doing when they happened. Then you can look at your diary to notice a pattern over time.

3. You’re experiencing medication overuse headaches.

If you take a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen or naproxen more than you should, you may start experiencing even more headaches. These medication overuse headaches (MOH) are a common result when people take these meds too often. And “too often” might not even be as often as you’d think; the American Migraine Foundation suggests the threshold is more than twice per week. You may also hear the term “rebound headaches” to describe these headaches. You have to be especially careful if you’re taking combination medications because you might wind up taking a dose that’s too high, which can cause other problems, too.

4. You want to try a different treatment.

Another reason to call your doctor and make an appointment: your migraine pain is getting worse, but your OTC treatment is no longer cutting it. It might be time to switch to prescription-strength pain medication, or a prescription medication designed to prevent migraines from occurring in the first place.

Prescription medications that are available to you include:


  • Prescription-strength NSAIDs: These can be more powerful than OTC NSAIDs and offer more relief.
  • Triptans: These drugs are intended to address headache pain, not prevent headaches. Meds in this category include sumatriptan (Imitrex), eletriptan (Relpax), rizatriptan (Maxalt), and zolmitriptan (Zomig).
  • Ergot alkaloids or ergotamine, such as Ergomar or Migranal: You would take this kind of drug to treat a headache that’s already started, not to prevent them from happening. However, it can cause blood vessels in the brain to narrow and cause potential side effects.
  • Opioid painkillers: These can effectively relieve pain; however, these drugs can be highly addictive and increase your risk of medication overuse headaches.
  • Blood pressure-lowering medications: These include beta blockers such as propranolol, or calcium channel blockers. These meds are aimed at prevention.
  • Anticonvulsants: An anticonvulsant seizure medication like valproic acid can be used to prevent migraines.
  • Antidepressants: Various types of antidepressants have been shown to ease pain associated with migraines.
  • Monoclonal antibodies: These are some of the newest drugs approved by the U.S. Food and Drug Administration (FDA) to treat migraine pain; the drug class includes the preventive medications erenumab (Aimovig), fremanezumab (Ajovy), galcanezumab (Emgality), and eptinezumab-jjmr (Vyepti) as well as two newer drugs designed to address acute pain, lasmiditan (Reyvow) and ubrogepant (Ubrelvy), both of which are available in tablet form.

There are also some combination drugs available, like Treximet, which combines a triptan and an NSAID to treat acute migraine pain.
Your doctor will want to discuss the pros and cons of these options. For example, some of them, like ergotamine and valproic acid, can have serious side effects or interact with other medications you might be taking. 

5. You experience worrisome changes.

If you keep a headache diary–or even if you don’t–you’re probably aware of what you typically experience during a migraine. You might recognize the early signs that one is brewing, and you’ll know if you are likely to become nauseated or dizzy.

However, if you experience certain symptoms unlike your usual ones, that could be a sign something serious is wrong. Watch out for these red flags:

  • Severe sharp headache that arrives with no warning
  • Headache after experiencing a head injury
  • A new type of headache unlike others you’ve experienced
  • A headache that gets worse if you’re lying down, coughing, or sneezing
  • Headache that comes with a fever, stiff neck, weakness or numbness, or confusion
  • Headaches that develop later in life, in your 40s and 50s

Here’s another reason why you shouldn’t blow off changes in symptoms: Research suggests people who have migraines with auras are at increased risk for stroke–and that’s especially true for women. You don’t want to miss a sign of something serious like an impending stroke by dismissing an early symptom.
The bottom line is any unusual developments in your pattern of migraines can justify a call to your doctor. And if your medication doesn’t seem effective, that’s another reason to schedule an appointment, as it might be time to take another approach. It’s also a good chance to ask your doctor about lifestyle changes or complementary therapies that could help.

Was this helpful?
24
  1. Acute Therapy: Why Not Over-the-Counter or Other Nonspecific
    Options? American Migraine Foundation.
    https://americanmigrainefoundation.org/resource-library/acute-therapy-why-not-over-the-counter-or-ot...
  2. Are the new migraine medications working? Harvard Health
    Letter. Harvard Medical School. https://www.health.harvard.edu/diseases-and-conditions/are-the-new-migraine-medications-working
  3. Bland A. Three signs you may need to see a neurologist for
    your headaches. Baylor College of Medicine.
    https://blogs.bcm.edu/2017/11/29/three-signs-may-need-see-neurologist-headaches/
  4. CGRP Inhibitors for Migraine Prevention: What Prescribers
    Need to Know. Cleveland Clinic.
    https://consultqd.clevelandclinic.org/cgrp-inhibitors-for-migraine-prevention-what-prescribers-need-...
  5. Dr. Shivang Joshi discusses alternative treatment methods
    that can help provide migraine relief. American Migraine Foundation. March 4,
    2018.
    https://americanmigrainefoundation.org/resource-library/non-pharmacological-approaches-to-migraine-m...
  6. Excedrin Migraine. U.S. National Library of Medicine Daily Med.
    https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=7ed841fb-a61c-4868-b4e5-4f2311a5e79c&type=display
  7. Excedrin Migraine Caplets Drug Facts. 
    https://www.excedrin.com/content/dam/cf-consumer-healthcare/excedrin/en_US/documents/MIGRAINE_DRUGFA...
  8. Headache: Hope Through Research. National Institute of
    Neurological Disorders and Stroke.
    https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Hope-Through-Research/Headache-Hope-...
  9. Headache Medicine Ergot-Derivative-Containing (Oral Route,
    Parenteral Route, Rectal Route). Mayo Clinic.
    https://www.mayoclinic.org/drugs-supplements/headache-medicine-ergot-derivative-containing-oral-rout...
  10. Holland S et al. Evidence-based guideline update: NSAIDs and
    other complementary treatments for episodic migraine prevention in adults:
    report of the Quality Standards Subcommittee of the American Academy of
    Neurology and the American Headache Society. Neurology. 2012;78(17):1346–1353.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335449/
  11. Kamin D. OTC: Wrapping Your Mind Around Migraine
    Medications. UC San Diego Health. https://health.ucsd.edu/news/features/Pages/2019-05-06-OTC-wrapping-your-mind-around-migraine-medications.aspx
  12. Migraine. Mayo Clinic.
    https://www.mayoclinic.org/diseases-conditions/migraine-headache/symptoms-causes/syc-20360201
  13. Migraine Facts. Migraine Research Foundation.
    https://migraineresearchfoundation.org/about-migraine/migraine-facts/
  14. Migraine Headaches. Columbia University Department of
    Neurology. http://www.columbianeurology.org/neurology/staywell/document.php?id=33942
  15. Migraine Headaches. Johns Hopkins Medicine.
    https://www.hopkinsmedicine.org/health/conditions-and-diseases/headache/migraine-headaches
  16. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for Acute
    Migraine Treatment. American Migraine Foundation.
    https://americanmigrainefoundation.org/resource-library/non-steroidal-anti-inflammatory-drugs-nsaids...
  17. Opioids and Migraine. American Headache Society.
    https://americanheadachesociety.org/news/opioids-migraine/
  18. Production of Excedrin Migraine Discontinued Until Further
    Notice. American Migraine Foundation.
    https://americanmigrainefoundation.org/resource-library/excedrin-migraine-discontinued/
  19. Reddy DS. The Pathophysiological and Pharmacological Basis
    of Current Drug Treatment of Migraine Headache. Expert Review of Clinical
    Pharmacology. 2013;6(3):271-288. https://www.medscape.com/viewarticle/804034_12
  20. Urits I, et al. CGRP Antagonists for the Treatment of
    Chronic Migraines: A Comprehensive Review. Current Pain and Headache Reports.
    2019 Mar 14;23(5):29. https://www.ncbi.nlm.nih.gov/pubmed/30874961
  21. Wells RE, et al. Complementary and alternative medicine use
    among adults with migraines/severe headaches. Headache. 2011;51(7):1087–1097.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627391/
  22. When you should worry about
    your headache. UCI Health. http://www.ucihealth.org/blog/2017/07/migraines
Medical Reviewer: William C. Lloyd III, MD, FACS
Last Review Date: 2022 Feb 17
View All Your Guide to Preventing Migraines Articles
THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Never ignore professional medical advice in seeking treatment because of something you have read on the site. If you think you may have a medical emergency, immediately call your doctor or dial 911.