How Often Do Colon Polyps Become Cancer?

Was this helpful?

Most colon cancers start as polyps. Those are small growths on the lining of the colon. However, most polyps do not become cancerous. Polyps are usually harmless. Some people have these growths scattered throughout their colon. Over time, though, cancer may start in certain polyps. 

Doctors find polyps during routine screenings, like a colonoscopy. It's hard to tell which polyps will progress to colon cancer. They must be removed and examined under a microscope. 

There are certain clues that help doctors figure out whether a polyp is likely to become cancer. These include the type of polyp, its growth pattern, and the location and size of the polyp. How abnormal the cells are is another clue.

Determining Cancer Risk

There is more than one type of colon polyp. The two most common types are:

Hyperplastic polyps: These are usually harmless and typically small. They are often found in the rectum, which is at the end of the colon.

Adenomas: These polyps could become cancer. Adenomas account for more than 66% of colon polyps. Still, most adenomas are harmless—only about 10% of adenomas turn into cancer. 

Not all adenomas are alike. Polyps with a sawtooth appearance are called serrated. Most serrated polyps are hyperplastic, but some are adenomas. People with a serrated adenoma are at greater risk for developing colon cancer. Serrated polyps account for up to 30% of all colon cancers.

Adenomas also have various growth patterns: 

  • About 80% are tubular. Tubular polyps have less than a 5% chance of becoming cancerous.

  • About 5 to 10% have finger-like projections. These are called villous polyps. They are the most serious type—about half of these growths are cancerous.

  • Up to 15% of adenomas are both tubular and villous, hence their name: tubulovillous. About 22% of tubulovillous adenomas become cancer.

Adenomas may be flat or look like a small bump on the colon wall. Others have a stalk and resemble a mushroom. Flat polyps more often become cancer.

Other Things to Consider

Whether a polyp will turn into cancer also depends on:

  • Location: Hyperplastic polyps are usually found in the rectum. They pose little risk. But, sometimes they grow in what's called the ascending colon. That's the first main part of the large intestine. Polyps that grow there are more likely to become cancer.

  • Size: Polyps also vary in size. Some are just a few millimeters. Others may grow to several centimeters (cm). Larger polyps are more likely to become cancer. In fact, polyps larger than 2.5 cm (equivalent to 1 inch) are five times more likely to be cancerous than those smaller than 1.5 cm. Larger adenomas are also more likely to have a more risky villous growth pattern.

  • Cells: Doctors also look at polyps (removed during colonoscopy) under a microscope to look for abnormal cells. The medical term for abnormal cells is dysplasia. Some polyps are only slightly abnormal. Others look much more like cancer cells. High-grade dysplasia greatly increases the likelihood of the polyp becoming colon cancer. People with polyps that have highly abnormal cells need more aggressive monitoring for the disease.

Was this helpful?
Medical Reviewer: William C. Lloyd III, MD, FACS
Last Review Date: 2020 Feb 13
THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Never ignore professional medical advice in seeking treatment because of something you have read on the site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

  1. Colon polyps. Mayo Clinic.

  2. Colon Polyps. The University of Texas MD Anderson Cancer Center.

  3. Colon Polyps. American College of Gastroenterology.

  4. Understanding Polyps and Their Treatment. American Society for Gastrointestinal Endoscopy.

  5. Understanding Your Pathology Report: Colon Polyps (Sessile or Traditional Serrated Adenomas). American Cancer Society.

  6. Fleming M, Ravula S, Tatishchev SF, Wang HL. Colorectal Carcinoma: Pathologic Aspects. J Gastrointest Oncol. 2012;3(3):153-173.

  7. What Is Colorectal Cancer? American Cancer Society.

  8. Michalopoulos G, Tzathas C. Serrated Polyps of Right Colon: Guilty or Innocent? Ann Gastroenterol. 2013;26(3):212-219.

  9. Screening Colonoscopy Adenoma Detection Rate. American Medical Association. 2013.

  10. Steinberg M. Colorectal Cancer Screening Guidelines Update. US Pharm. 2012.;37(12):22-26.

  11. Amersi F, Agustin M, Ko CY. Colorectal Cancer: Epidemiology, Risk Factors, and Health Services. Clin Colon Rectal Surg. 2005;18(3):133-140.

  12. Shussman N, Wexner SD. Colorectal Polyps and Polyposis Syndromes. Gastroenterol Rep. (2014) 1-15.