QUESTION & ANSWER
Q: How much diphenhydramine can I take?

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A:

Diphenhydramine HCl comes in 25 mg and 50 mg strengths (Benadryl is a common brand). For adults and teens, the diphenhydramine dosage is 25 to 50 mg every 4 to 6 hours. The maximum amount you should take in one day is 300 mg. Keep in mind, taking higher doses can increase the risk of side effects, including drowsiness.

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  1. Diphenhydramine. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682539.html 
  2. Diphenhydramine Prescribing Information. Drugs.com. https://www.drugs.com/pro/diphenhydramine.html