Q: How much diphenhydramine can I take?

Was this helpful?

Diphenhydramine HCl comes in 25 mg and 50 mg strengths (Benadryl is a common brand). For adults and teens, the diphenhydramine dosage is 25 to 50 mg every 4 to 6 hours. The maximum amount you should take in one day is 300 mg. Keep in mind, taking higher doses can increase the risk of side effects, including drowsiness.

Was this helpful?
  1. Diphenhydramine. U.S. National Library of Medicine. 
  2. Diphenhydramine Prescribing Information.
Explore Allergies
Recommended Reading
Health Spotlight
Next Up
Answers to Your Health Questions
Trending Videos