Dr. Zain Khalpey, MD

Cardiothoracic Surgery  ·  
Male  ·  
Age 45
(3)
Insurances Accepted  ·  Save
Dr. Zain Khalpey, MD
"Zain Khalpey, MD, PhD, FACS, FETCS, associate professor of surgery at the University of Arizona College of Medicine – Tucson is the Tony S. Marnell, Sr. Endowed Chair for Research in Cardiothoracic Surgery. He serves as Surgical Director of the Mechanical Circulatory Support and Artificial Heart Programs and Co-Director of the Heart Transplant and Perfusion Sciences Programs at Banner - University Medical Center Tucson. After finishing his medical education at the University of London, he continued his clinical training at prestigious clinical institutions throughout the United States, such as the Brigham & Women's Hospital at Harvard Medical School in Boston and New York Presbyterian Hospital at Columbia University in New York. Dr. Khalpeys research culminated in a PhD obtained through joint work at the University of Gdansk, Mayo Clinic, Harvard University, and Imperial College in the United Kingdom. In 2016 Dr. Khalpey was awarded the Distinguished Fulbright Chair in Medical Sciences (Europe). His major research focus is on translation of precision metabolomics in cardiac surgery. In particular: (1) to modulate progression of valve disease, (2) metabolic reconditioning or salvage of marginal organs for transplant and (3) evaluating the bioenergetics and sequelae of myocardial recovery when using regenerative medicine strategies with mechanical circulatory support. His approach to basic science research is ultimately geared towards clinical translation for myocardial recovery. As a surgeon scientist Dr. Khalpey uses his clinical career to inspire his research to enhance the translation to patient care."

Risks associated with the TAVR procedure include death, stroke and major bleeding

Important Risk Information for Patients

Indications:

The Edwards SAPIEN 3 transcatheter heart valve, model 9600TFX, and accessories are indicated for relief of aortic stenosis in patients with symptomatic heart disease due to severe native calcific aortic stenosis who are judged by a Heart Team, including a cardiac surgeon, to be at intermediate or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 3% at 30 days, based on the Society of Thoracic Surgeons (STS) risk score and other clinical co-morbidities unmeasured by the STS risk calculator).

The Edwards SAPIEN 3 transcatheter heart valve, model 9600TFX, and accessories are indicated for patients with symptomatic heart disease due to failure (stenosed, insufficient, or combined) of a surgical bioprosthetic aortic or mitral valve who are judged by a heart team, including a cardiac surgeon, to be at high or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 8% at 30 days, based on the STS risk score and other clinical co-morbidities unmeasured by the STS risk calculator).

Contraindications (Who should not use):

The Edwards SAPIEN 3 transcatheter heart valve and delivery system should not be used in patients who:

  • Cannot tolerate medications that thin the blood or prevent blood clots from forming.
  • Have an active infection in the heart or elsewhere.

Warnings:

  • There may be an increased risk of stroke in transcatheter aortic valve replacement procedures, compared to other standard treatments for aortic stenosis in the high or greater risk population.
  • If an incorrect valve size for your anatomy is used, it may lead to heart injury, valve leakage, movement, or dislodgement.
  • Patients should talk to their doctor if they have significant heart disease, a mitral valve device or are allergic to chromium, nickel, molybdenum, manganese, copper, silicon, and/or polymeric materials.
  • The SAPIEN 3 valve may not last as long in patients whose bodies do not process calcium normally.
  • During the procedure, your doctors should monitor the dye used in the body; if used in excess it could lead to kidney damage. X-ray guidance used during the procedure may cause injury to the skin, which may be painful, damaging, and long-lasting.
  • Transcatheter aortic heart valve patients should take medications that thin the blood or prevent blood clots from forming, except when likely to have an adverse reaction, as determined by their physician. The Edwards SAPIEN 3 transcatheter heart valve has not been tested for use without medications that thin the blood or prevent blood clots from forming.

Precautions:

The long-term durability of the Edwards SAPIEN 3 transcatheter heart valve is not known at this time. Regular medical follow-up is recommended to evaluate how well a patient’s heart valve is performing. Safety, performance, and durability of the SAPIEN 3 valve has not been established for placement inside a previously implanted transcatheter valve.

The safety and effectiveness of the transcatheter heart valve is also not known for patients who have:

  • An aortic heart valve that is not calcified, contains only one or two leaflets, has leaflets with large pieces of calcium that may block the vessels that supply blood to the heart or in which the main problem is that the valve leaks.
  • Previous prosthetic ring in any position.
  • Previous atrial septal occlude.
  • A heart that does not pump well, has thickening of the heart muscle, with or without blockage, unusual ultrasound images of the heart that could represent irregularities such as a blood clot, a diseased mitral valve that is calcified or leaking, or Gorlin syndrome, a condition that affects many areas of the body and increases the risk of developing various cancers and tumors.
  • Low white, red or platelet blood cell counts, or history of bleeding because the blood does not clot properly.
  • Diseased, abnormal or irregularly shaped vessels leading to the heart. Vessels which are heavily diseased or too small for associated delivery devices, or a large amount of calcification at the point of entry.
  • Allergies to blood-thinning medications or dye injected during the procedure.
  • For a valve in valve procedure, there is a risk of leakage if the previously implanted tissue valve is not securely in place or if it is damaged. There is also the possibility that a partially detached valve leaflet from the previously implanted valve could block a blood vessel.
  • Additional pre-procedure imaging will be completed to evaluate proper sizing.

Potential risks associated with the procedure include:

  • Death, stroke, paralysis (loss of muscle function), permanent disability, or severe bleeding.
  • Risks to the heart, including heart attack or heart failure, a heart that does not pump well, irregular heartbeat that may result in a need for a permanent pacemaker, chest pain, heart murmur, false aneurysm, recurring aortic stenosis(narrowing), too much fluid around the heart, injury to the structure of the heart.
  • Risks to your lungs or breathing, including difficulty breathing, fainting, buildup of fluid in or around the lungs, weakness or inability to exercise.
  • Risks involving bleeding or your blood supply, including formation of a blood clot, high or low blood pressure, limited blood supply, a decrease in red blood cells, or abnormal lab values, bleeding in the abdominal cavity, collection of blood under the skin.
  • Additional risks, including life-threatening infection, dislodgement of calcified material, air embolism (air bubbles in the blood vessels), poor kidney function or failure, nerve injury, fever, allergic reaction to anesthesia or dye, reoperation, pain, infection or bleeding at incision sites, or swelling.

Additional potential risks specifically associated with the use of the heart valve include:

  • Valve movement after deployment, blockage or disruption of blood flow through the heart, need for additional heart surgery and possible removal of the SAPIEN 3 valve, a blood clot that requires treatment, damage to the valve (e.g., wear, breakage, recurring aortic stenosis), nonstructural valve dysfunction (e.g., leakage, inappropriate sizing or positioning, blockage, excess tissue in growth, blood cell damage, etc.) or mechanical failure of the delivery system and/or accessories.

CAUTION: Federal (United States) law restricts these devices to sale by or on the order of a physician.

Edwards, Edwards Lifesciences, the stylized E logo, Edwards SAPIEN, Edwards SAPIEN 3, SAPIEN, and SAPIEN 3 are trademarks of Edwards Lifesciences Corporation. All other trademarks are the property of their respective owners.

© 2017 Edwards Lifesciences Corporation. All rights reserved. PP--US-2507 v1.0

Edwards Lifesciences One Edwards Way, Irvine CA 92614 USA edwards.com

1501 N CAMPBELL AVE FL 5

Tucson, AZ 85724

Contact Information

(520) 694-8888

Dr. Zain Khalpey, MD

Dr. Zain Khalpey, MD

Accepted insurance

  • Aetna
  • Blue Cross Blue Shield
  • Cigna
  • First Health (Coventry Health Care)
  • MultiPlan

*Please verify this information when scheduling an appointment.

Background Check

Healthgrades does not collect malpractice information for Arizona
No disciplinary actions found for the years we collect data
No board actions found for the years we collect data
Learn more about background checks

Experience Check

Check Dr. Khalpey's experience treating your condition or procedure

Dr. Khalpey's Top Procedures and Conditions

Treatment Frequency
Heart Defect Repair
high
high

Treatment Frequency

Dr. Khalpey performs Heart Defect Repair more than 78% of his peers

Dr. Khalpey performs this procedure more than 78% of his peers

Heart Disease
normal
normal

Treatment Frequency

Dr. Khalpey treats Heart Disease more than 56% of his peers

Dr. Khalpey treats this condition more than 56% of his peers

Coronary Artery Disease (CAD)
normal
normal

Treatment Frequency

Dr. Khalpey treats Coronary Artery Disease (CAD) more than 53% of his peers

Dr. Khalpey treats this condition more than 53% of his peers

Rating Includes other areas of care:

  • Coronary Artery Calcification
  • Coronary Artery Disease, Autosomal Dominant 1
  • Coronary Artery Disease, Autosomal Dominant 2

Dr. Khalpey's conditions and procedures:

Ablation for Treatment of Cardiac Arrhythmias
Abscess or Cyst Drainage or Aspiration
Abscess or Fluid Incision and Drainage
Aneurysm
Aneurysm of Heart
Angina and Acute Coronary Syndrome
Aortic Aneurysm
Aortic Dilation
Aortic Dissection
Aortic Embolism and Thrombosis
Aortic Repair, Open or Repair of Arterial Aneurysm, Open
Aortic Stenosis
Aortic Valve Disease
Aortic Valve Regurgitation
Aortic Valve Surgery
Arrhythmias
Ascending Thoracic Aortic Aneurysm
Atrial Arrhythmia
Atrial Cardiomyopathy With Heart Block
Atrial Fibrillation
Atrial Flutter
Atrial Myxoma
Atrial Myxoma, Familial
Atrial Septal Defect
Atrial Septal Defect Atrioventricular Conduction
Benign Tumor
Bicuspid Aortic Valve
Cancer
Cardiac Arrest
Cardiac Catheterization (incl. Coronary Angiography)
Cardiac Defects
Cardiac Electrophysiology
Cardiac MRI (Magnetic Resonance Imaging) of Heart or Chest
Cardiac Sources of Embolism
Cardiac Tamponade
Cardiomegaly
Cardiomyopathy
Cardiomyopathy - Renal Anomalies
Cardiovascular Disease
Cardioverter-Defibrillator or Pacemaker Insertion, Removal or Repair
Carotid Artery Disease
Chest CT (incl. Heart and Lungs)
Coarctation of the Aorta
Congenital Heart Defects
Congenital Heart Disease
Congestive Heart Failure
Coronary Artery Bypass Graft (CABG) Surgery
Coronary Artery Bypass With Robotic Assistance
Coronary Artery Disease (CAD)
Coronary Cathertization With Robotic Assistance
Decortication and Pleurectomy
Endocarditis
Endovascular Repair of Aorta
Endovascular Repair of Thoracic Aorta
Esophageal Diseases
Esophageal Surgery
Head and Neck Surgery
Heart Attack (Acute Myocardial Infarction)
Heart Defect Repair
Heart Disease
Heart Disease in Women
Heart Failure
Heart Palpitations
Heart Surgery
Heart Transplant Rejection
Heart Valve Diseases
Hernia Repair
Impella Device
Incision and Removal of Foreign Object
Lung Neoplasms, Not Specified as Malignant
Lung Surgery
Lymph Node Biopsy or Excision
Maze Procedure
Mitral Valve Disease
Mitral Valve Prolapse
Mitral Valve Regurgitation
Mitral Valve Stenosis
Mitral Valve Surgery
Neuroendocrine Tumors
Non-Coronary Angioplasty, Atherectomy, and Stenting
Pericardial Disease
Peripheral Arterial Aneurysm
Peripheral Arterial Aneurysm and Dissection
Peripheral Artery Catheterization
Port Placements or Replacements
Pulmonary Disease
Pulmonary Embolism
Pulmonary Hypertension
Pulmonary Valve Disease
Pulmonary Vascular Disease
Ruptured Aortic Aneurysm
Secondary Hypertension
Septal Defect
Thoracentesis
Thrombosis
Tracheal Surgery
Transplanted Organ Rejection
Tricuspid Valve Disease
Tricuspid Valve Incompetence
Tricuspid Valve Stenosis
Tricuspid Valve Surgery
Valve Repair or Replacement (Aortic, Mitral, Tricuspid, and Pulmonary)
Valvular Regurgitation
Vascular Disease
Vascular Surgical Procedure
Ventricular Arrhythmia
Ventricular Assist Device
Ventricular Enlargement
Ventricular Fibrillation
Ventricular Septal Defect
Ventricular Septal Rupture
Video-Assisted Thoracoscopic Surgery (VATS) or Thoracotomy

About Me

Care Philosophy

We believe in personalized surgery, not treating patients like they are in a factory and individualizing their care and concerns, tailoring their surgical therapy and offering the best of personalized medicine and surgery and predictive smart medicine

Specialties

  • Cardiothoracic Surgery
  • Adult Cardiac Surgery
  • Advanced Heart Failure & Transplant Cardiology
  • Cardiac Surgery

Education

  • St Mary's Hospital Medical School, Imperial College
    Residency Hospital
  • Guy's, King's & St Thomas's School Of Medicine
    Residency Hospital
  • 2013
    Columbia University / College Of Physicians and Surgeons
    Fellowship Hospital
    2013
  • 2012
    Brigham & Women's Hosp Harvard Med Sch
    Fellowship Hospital
    2012
  • 1998
    University Of London / United Medical and Dental Schools Of Guy's and Saint Thomas's Hospitals
    Medical School
    1998
  • 1995
    St Mary's Hospital Medical School, Imperial College
    Medical School
    1995

Languages

  • French
  • English

Dr. Khalpey's Reviews

Likelihood to recommend Dr. Khalpey

5.0

Based on 3 reviews

5 Stars
100%
(3)
4 Stars
0%
(0)
3 Stars
0%
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2 Stars
0%
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1 Star
0%
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What People Say About Dr. Zain Khalpey, MD
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I would definitely recommend Dr. Khalphey to all my family and friends. He is the most caring and passionate Doctor that I have ever met. He works very aggressive to do everything possible to make sure everything possible is being done. To Dr. Khalpey his team of Doctors and the entire ICU...Read More
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Locations

Insurance accepted

Accepted insurance can change. Please double-check when making an appointment.

Aetna
Aetna HMO
Aetna Savings Plus of AZ
Choice Plus POS II
Blue Cross Blue Shield
Blue Card PPO
Cigna
Cigna HMO
Cigna PPO
Open Access Plus
First Health (Coventry Health Care)
First Health (Coventry Health Care) PPO
MultiPlan
MultiPlan PPO
PHCS Network PPO

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