Dr. Zain Khalpey, MD

Cardiothoracic Surgery  ·  
Male  ·  
Age 45
(3)
Insurances Accepted  ·  Save
Dr. Zain Khalpey, MD
"Zain Khalpey, MD, PhD, FACS, FETCS, associate professor of surgery at the University of Arizona College of Medicine – Tucson is the Tony S. Marnell, Sr. Endowed Chair for Research in Cardiothoracic Surgery. He serves as Surgical Director of the Mechanical Circulatory Support and Artificial Heart Programs and Co-Director of the Heart Transplant and Perfusion Sciences Programs at Banner - University Medical Center Tucson. After finishing his medical education at the University of London, he continued his clinical training at prestigious clinical institutions throughout the United States, such as the Brigham & Women's Hospital at Harvard Medical School in Boston and New York Presbyterian Hospital at Columbia University in New York. Dr. Khalpeys research culminated in a PhD obtained through joint work at the University of Gdansk, Mayo Clinic, Harvard University, and Imperial College in the United Kingdom. In 2016 Dr. Khalpey was awarded the Distinguished Fulbright Chair in Medical Sciences (Europe). His major research focus is on translation of precision metabolomics in cardiac surgery. In particular: (1) to modulate progression of valve disease, (2) metabolic reconditioning or salvage of marginal organs for transplant and (3) evaluating the bioenergetics and sequelae of myocardial recovery when using regenerative medicine strategies with mechanical circulatory support. His approach to basic science research is ultimately geared towards clinical translation for myocardial recovery. As a surgeon scientist Dr. Khalpey uses his clinical career to inspire his research to enhance the translation to patient care."

Risks associated with the TAVR procedure include death, stroke and major bleeding

Important Risk Information for Patients

Indications:

The Edwards SAPIEN 3 transcatheter heart valve, model 9600TFX, and accessories are indicated for relief of aortic stenosis in patients with symptomatic heart disease due to severe native calcific aortic stenosis who are judged by a Heart Team, including a cardiac surgeon, to be at intermediate or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 3% at 30 days, based on the Society of Thoracic Surgeons (STS) risk score and other clinical co-morbidities unmeasured by the STS risk calculator).

The Edwards SAPIEN 3 transcatheter heart valve, model 9600TFX, and accessories are indicated for patients with symptomatic heart disease due to failure (stenosed, insufficient, or combined) of a surgical bioprosthetic aortic or mitral valve who are judged by a heart team, including a cardiac surgeon, to be at high or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 8% at 30 days, based on the STS risk score and other clinical co-morbidities unmeasured by the STS risk calculator).

Contraindications (Who should not use):

The Edwards SAPIEN 3 transcatheter heart valve and delivery system should not be used in patients who:

  • Cannot tolerate medications that thin the blood or prevent blood clots from forming.
  • Have an active infection in the heart or elsewhere.

Warnings:

  • There may be an increased risk of stroke in transcatheter aortic valve replacement procedures, compared to other standard treatments for aortic stenosis in the high or greater risk population.
  • If an incorrect valve size for your anatomy is used, it may lead to heart injury, valve leakage, movement, or dislodgement.
  • Patients should talk to their doctor if they have significant heart disease, a mitral valve device or are allergic to chromium, nickel, molybdenum, manganese, copper, silicon, and/or polymeric materials.
  • The SAPIEN 3 valve may not last as long in patients whose bodies do not process calcium normally.
  • During the procedure, your doctors should monitor the dye used in the body; if used in excess it could lead to kidney damage. X-ray guidance used during the procedure may cause injury to the skin, which may be painful, damaging, and long-lasting.
  • Transcatheter aortic heart valve patients should take medications that thin the blood or prevent blood clots from forming, except when likely to have an adverse reaction, as determined by their physician. The Edwards SAPIEN 3 transcatheter heart valve has not been tested for use without medications that thin the blood or prevent blood clots from forming.

Precautions:

The long-term durability of the Edwards SAPIEN 3 transcatheter heart valve is not known at this time. Regular medical follow-up is recommended to evaluate how well a patient’s heart valve is performing. Safety, performance, and durability of the SAPIEN 3 valve has not been established for placement inside a previously implanted transcatheter valve.

The safety and effectiveness of the transcatheter heart valve is also not known for patients who have:

  • An aortic heart valve that is not calcified, contains only one or two leaflets, has leaflets with large pieces of calcium that may block the vessels that supply blood to the heart or in which the main problem is that the valve leaks.
  • Previous prosthetic ring in any position.
  • Previous atrial septal occlude.
  • A heart that does not pump well, has thickening of the heart muscle, with or without blockage, unusual ultrasound images of the heart that could represent irregularities such as a blood clot, a diseased mitral valve that is calcified or leaking, or Gorlin syndrome, a condition that affects many areas of the body and increases the risk of developing various cancers and tumors.
  • Low white, red or platelet blood cell counts, or history of bleeding because the blood does not clot properly.
  • Diseased, abnormal or irregularly shaped vessels leading to the heart. Vessels which are heavily diseased or too small for associated delivery devices, or a large amount of calcification at the point of entry.
  • Allergies to blood-thinning medications or dye injected during the procedure.
  • For a valve in valve procedure, there is a risk of leakage if the previously implanted tissue valve is not securely in place or if it is damaged. There is also the possibility that a partially detached valve leaflet from the previously implanted valve could block a blood vessel.
  • Additional pre-procedure imaging will be completed to evaluate proper sizing.

Potential risks associated with the procedure include:

  • Death, stroke, paralysis (loss of muscle function), permanent disability, or severe bleeding.
  • Risks to the heart, including heart attack or heart failure, a heart that does not pump well, irregular heartbeat that may result in a need for a permanent pacemaker, chest pain, heart murmur, false aneurysm, recurring aortic stenosis(narrowing), too much fluid around the heart, injury to the structure of the heart.
  • Risks to your lungs or breathing, including difficulty breathing, fainting, buildup of fluid in or around the lungs, weakness or inability to exercise.
  • Risks involving bleeding or your blood supply, including formation of a blood clot, high or low blood pressure, limited blood supply, a decrease in red blood cells, or abnormal lab values, bleeding in the abdominal cavity, collection of blood under the skin.
  • Additional risks, including life-threatening infection, dislodgement of calcified material, air embolism (air bubbles in the blood vessels), poor kidney function or failure, nerve injury, fever, allergic reaction to anesthesia or dye, reoperation, pain, infection or bleeding at incision sites, or swelling.

Additional potential risks specifically associated with the use of the heart valve include:

  • Valve movement after deployment, blockage or disruption of blood flow through the heart, need for additional heart surgery and possible removal of the SAPIEN 3 valve, a blood clot that requires treatment, damage to the valve (e.g., wear, breakage, recurring aortic stenosis), nonstructural valve dysfunction (e.g., leakage, inappropriate sizing or positioning, blockage, excess tissue in growth, blood cell damage, etc.) or mechanical failure of the delivery system and/or accessories.

CAUTION: Federal (United States) law restricts these devices to sale by or on the order of a physician.

Edwards, Edwards Lifesciences, the stylized E logo, Edwards SAPIEN, Edwards SAPIEN 3, SAPIEN, and SAPIEN 3 are trademarks of Edwards Lifesciences Corporation. All other trademarks are the property of their respective owners.

© 2017 Edwards Lifesciences Corporation. All rights reserved. PP--US-2507 v1.0

Edwards Lifesciences One Edwards Way, Irvine CA 92614 USA edwards.com

1501 N CAMPBELL AVE FL 5

Tucson, AZ 85724

Contact Information

(520) 694-8888

Dr. Zain Khalpey, MD

Dr. Zain Khalpey, MD

Accepted insurance

  • Aetna
  • Blue Cross Blue Shield
  • Cigna
  • First Health (Coventry Health Care)
  • MultiPlan

*Please verify this information when scheduling an appointment.

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Top Care Areas

See how frequently Dr. Khalpey performs your care needs compared to other doctors.

Heart Defect Repair
normal
more than 75% of peers
Heart Disease
normal
more than 57% of peers
Vascular Disease
normal
more than 55% of peers

Dr. Khalpey's percentages are based on the rate of treatment compared to peers nationwide from insurance data. Learn more info about our data and this Top Care Areas component.

Dr. Khalpey's bio

This content was provided by Dr. Khalpey "Zain Khalpey, MD, PhD, FACS, FETCS, associate professor of surgery at the University of Arizona College of Medicine – Tucson is the Tony S. Marnell, Sr. Endowed Chair for Research in Cardiothoracic Surgery. He serves as Surgical Director of the Mechanical Circulatory Support and Artificial Heart Programs and Co-Director of the Heart Transplant and Perfusion Sciences Programs at Banner - University Medical Center Tucson. After finishing his medical education at the University of London, he continued his clinical training at prestigious clinical institutions throughout the United States, such as the Brigham & Women's Hospital at Harvard Medical School in Boston and New York Presbyterian Hospital at Columbia University in New York. Dr. Khalpeys research culminated in a PhD obtained through joint work at the University of Gdansk, Mayo Clinic, Harvard University, and Imperial College in the United Kingdom. In 2016 Dr. Khalpey was awarded the Distinguished Fulbright Chair in Medical Sciences (Europe). His major research focus is on translation of precision metabolomics in cardiac surgery. In particular: (1) to modulate progression of valve disease, (2) metabolic reconditioning or salvage of marginal organs for transplant and (3) evaluating the bioenergetics and sequelae of myocardial recovery when using regenerative medicine strategies with mechanical circulatory support. His approach to basic science research is ultimately geared towards clinical translation for myocardial recovery. As a surgeon scientist Dr. Khalpey uses his clinical career to inspire his research to enhance the translation to patient care."
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Care Philosophy

This content was provided by Dr. Khalpey "We believe in personalized surgery, not treating patients like they are in a factory and individualizing their care and concerns, tailoring their surgical therapy and offering the best of personalized medicine and surgery and predictive smart medicine"

11  Specialties

  • Cardiothoracic Surgery
  • Adult Cardiac Surgery
  • Advanced Heart Failure & Transplant Cardiology
  • Cardiac Surgery
  • Cardiology Research
  • Clinical Research
  • Congenital Cardiac Surgery
  • Minimally Invasive Cardiac Surgery
  • Regenerative Medicine
  • Thoracic Surgery
  • Transplant Surgery

0  Board Certifications

Dr. Khalpey does not have any board certifications listed.

75  Conditions Treated

  • Aneurysm
  • Aneurysm of Heart
  • Angina and Acute Coronary Syndrome
  • Aortic Aneurysm
  • Aortic Dilation
  • Aortic Dissection
  • Aortic Embolism and Thrombosis
  • Aortic Stenosis
  • Aortic Valve Disease
  • Aortic Valve Regurgitation
  • Arrhythmias
  • Ascending Thoracic Aortic Aneurysm
  • Atrial Arrhythmia
  • Atrial Cardiomyopathy With Heart Block
  • Atrial Fibrillation
  • Atrial Flutter
  • Atrial Myxoma
  • Atrial Myxoma, Familial
  • Atrial Septal Defect
  • Atrial Septal Defect Atrioventricular Conduction
  • Benign Tumor
  • Bicuspid Aortic Valve
  • Cancer
  • Cardiac Arrest
  • Cardiac Defects
  • Cardiac Sources of Embolism
  • Cardiac Tamponade
  • Cardiomegaly
  • Cardiomyopathy
  • Cardiomyopathy - Renal Anomalies
  • Cardiovascular Disease
  • Carotid Artery Disease
  • Coarctation of the Aorta
  • Congenital Heart Defects
  • Congenital Heart Disease
  • Congestive Heart Failure
  • Coronary Artery Disease (CAD)
  • Endocarditis
  • Esophageal Diseases
  • Heart Attack (Acute Myocardial Infarction)
  • Heart Disease
  • Heart Disease in Women
  • Heart Failure
  • Heart Palpitations
  • Heart Transplant Rejection
  • Heart Valve Diseases
  • Lung Neoplasms, Not Specified as Malignant
  • Mitral Valve Disease
  • Mitral Valve Prolapse
  • Mitral Valve Regurgitation
  • Mitral Valve Stenosis
  • Neuroendocrine Tumors
  • Pericardial Disease
  • Peripheral Arterial Aneurysm
  • Peripheral Arterial Aneurysm and Dissection
  • Pulmonary Disease
  • Pulmonary Embolism
  • Pulmonary Hypertension
  • Pulmonary Valve Disease
  • Pulmonary Vascular Disease
  • Ruptured Aortic Aneurysm
  • Secondary Hypertension
  • Septal Defect
  • Thrombosis
  • Transplanted Organ Rejection
  • Tricuspid Valve Disease
  • Tricuspid Valve Incompetence
  • Tricuspid Valve Stenosis
  • Valvular Regurgitation
  • Vascular Disease
  • Ventricular Arrhythmia
  • Ventricular Enlargement
  • Ventricular Fibrillation
  • Ventricular Septal Defect
  • Ventricular Septal Rupture
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38  Procedures

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Background Check

Malpractice Claims not available

Healthgrades does not collect malpractice information for Arizona.

0 Sanctions

No sanctions history found for the years that Healthgrades collects data.

0 Board Actions

No board actions found for the years that Healthgrades collects data.

Education

  • St Mary's Hospital Medical School, Imperial College
    Medical School | Graduated 1995
  • University of London / United Medical And Dental Schools of Guy's And Saint Thomas's Hospitals
    Medical School | Graduated 1998
  • Guy's, King's & St Thomas's School of Medicine
    Residency Hospital | Completed
  • St Mary's Hospital Medical School, Imperial College
    Residency Hospital | Completed
  • Brigham & Women's Hosp Harvard Med Sch
    Fellowship Hospital | Completed 2012
  • Columbia University / College of Physicians And Surgeons
    Fellowship Hospital | Completed 2013

Awards & Recognition

Awards & Honors

Dr. Khalpey has no awards or honors listed.

Media & Publications

Dr. Khalpey has no media or publications listed.

Languages Spoken

  • English
  • French

Memberships & Professional Affiliations

Dr. Khalpey does not have any memberships or affiliations listed. If you are Dr. Khalpey and would like to add memberships or affiliations, please update your profile.

Dr. Khalpey's Reviews

Likelihood to recommend Dr. Khalpey

5.0

Based on 3 reviews

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What People Say About Dr. Zain Khalpey, MD
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I would definitely recommend Dr. Khalphey to all my family and friends. He is the most caring and passionate Doctor that I have ever met. He works very aggressive to do everything possible to make sure everything possible is being done. To Dr. Khalpey his team of Doctors and the entire ICU...Read More
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Gloria in Phoenix, AZ – Mar 27, 2017
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Now Accepting New Patients

Dr. Khalpey accepts 5 insurance carriers

  • Aetna
    Aetna HMO
    Aetna Savings Plus of AZ
    Choice Plus POS II
  • Blue Cross Blue Shield
    Blue Card PPO
  • Cigna
    Cigna HMO
    Cigna PPO
    Open Access Plus
  • First Health (Coventry Health Care)
    First Health (Coventry Health Care) PPO
  • MultiPlan
    MultiPlan PPO
    PHCS Network PPO
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