Dr. Murali Dharan, MD is a cardiothoracic surgery specialist in Concord, CA. He specializes in cardiothoracic surgery and vascular surgery.
East Bay Cardiovascular & Thoracic Associates
2222 East St Ste 375
Concord, CA 94520
(925) 676-2600
Insurance Accepted
- Aetna
- Blue Cross Blue Shield
- Blue Cross Blue Shield of California
- Blue Shield of California
- Cigna
- Health Net of California
- Humana
- Kaiser Permanente
- MultiPlan
- + 3 More
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Risks associated with the TAVR procedure include death, stroke and major bleeding
Important Risk Information for Patients
Indications:
The Edwards SAPIEN 3 transcatheter heart valve, model 9600TFX, and accessories are indicated for relief of aortic stenosis in patients with symptomatic heart disease due to severe native calcific aortic stenosis who are judged by a Heart Team, including a cardiac surgeon, to be at intermediate or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 3% at 30 days, based on the Society of Thoracic Surgeons (STS) risk score and other clinical co-morbidities unmeasured by the STS risk calculator).
The Edwards SAPIEN 3 transcatheter heart valve, model 9600TFX, and accessories are indicated for patients with symptomatic heart disease due to failure (stenosed, insufficient, or combined) of a surgical bioprosthetic aortic or mitral valve who are judged by a heart team, including a cardiac surgeon, to be at high or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 8% at 30 days, based on the STS risk score and other clinical co-morbidities unmeasured by the STS risk calculator).
Contraindications (Who should not use):
The Edwards SAPIEN 3 transcatheter heart valve and delivery system should not be used in patients who:
- Cannot tolerate medications that thin the blood or prevent blood clots from forming.
- Have an active infection in the heart or elsewhere.
Warnings:
- There may be an increased risk of stroke in transcatheter aortic valve replacement procedures, compared to other standard treatments for aortic stenosis in the high or greater risk population.
- If an incorrect valve size for your anatomy is used, it may lead to heart injury, valve leakage, movement, or dislodgement.
- Patients should talk to their doctor if they have significant heart disease, a mitral valve device or are allergic to chromium, nickel, molybdenum, manganese, copper, silicon, and/or polymeric materials.
- The SAPIEN 3 valve may not last as long in patients whose bodies do not process calcium normally.
- During the procedure, your doctors should monitor the dye used in the body; if used in excess it could lead to kidney damage. X-ray guidance used during the procedure may cause injury to the skin, which may be painful, damaging, and long-lasting.
- Transcatheter aortic heart valve patients should take medications that thin the blood or prevent blood clots from forming, except when likely to have an adverse reaction, as determined by their physician. The Edwards SAPIEN 3 transcatheter heart valve has not been tested for use without medications that thin the blood or prevent blood clots from forming.
Precautions:
The long-term durability of the Edwards SAPIEN 3 transcatheter heart valve is not known at this time. Regular medical follow-up is recommended to evaluate how well a patient’s heart valve is performing. Safety, performance, and durability of the SAPIEN 3 valve has not been established for placement inside a previously implanted transcatheter valve.
The safety and effectiveness of the transcatheter heart valve is also not known for patients who have:
- An aortic heart valve that is not calcified, contains only one or two leaflets, has leaflets with large pieces of calcium that may block the vessels that supply blood to the heart or in which the main problem is that the valve leaks.
- Previous prosthetic ring in any position.
- Previous atrial septal occlude.
- A heart that does not pump well, has thickening of the heart muscle, with or without blockage, unusual ultrasound images of the heart that could represent irregularities such as a blood clot, a diseased mitral valve that is calcified or leaking, or Gorlin syndrome, a condition that affects many areas of the body and increases the risk of developing various cancers and tumors.
- Low white, red or platelet blood cell counts, or history of bleeding because the blood does not clot properly.
- Diseased, abnormal or irregularly shaped vessels leading to the heart. Vessels which are heavily diseased or too small for associated delivery devices, or a large amount of calcification at the point of entry.
- Allergies to blood-thinning medications or dye injected during the procedure.
- For a valve in valve procedure, there is a risk of leakage if the previously implanted tissue valve is not securely in place or if it is damaged. There is also the possibility that a partially detached valve leaflet from the previously implanted valve could block a blood vessel.
- Additional pre-procedure imaging will be completed to evaluate proper sizing.
Potential risks associated with the procedure include:
- Death, stroke, paralysis (loss of muscle function), permanent disability, or severe bleeding.
- Risks to the heart, including heart attack or heart failure, a heart that does not pump well, irregular heartbeat that may result in a need for a permanent pacemaker, chest pain, heart murmur, false aneurysm, recurring aortic stenosis(narrowing), too much fluid around the heart, injury to the structure of the heart.
- Risks to your lungs or breathing, including difficulty breathing, fainting, buildup of fluid in or around the lungs, weakness or inability to exercise.
- Risks involving bleeding or your blood supply, including formation of a blood clot, high or low blood pressure, limited blood supply, a decrease in red blood cells, or abnormal lab values, bleeding in the abdominal cavity, collection of blood under the skin.
- Additional risks, including life-threatening infection, dislodgement of calcified material, air embolism (air bubbles in the blood vessels), poor kidney function or failure, nerve injury, fever, allergic reaction to anesthesia or dye, reoperation, pain, infection or bleeding at incision sites, or swelling.
Additional potential risks specifically associated with the use of the heart valve include:
- Valve movement after deployment, blockage or disruption of blood flow through the heart, need for additional heart surgery and possible removal of the SAPIEN 3 valve, a blood clot that requires treatment, damage to the valve (e.g., wear, breakage, recurring aortic stenosis), nonstructural valve dysfunction (e.g., leakage, inappropriate sizing or positioning, blockage, excess tissue in growth, blood cell damage, etc.) or mechanical failure of the delivery system and/or accessories.
CAUTION: Federal (United States) law restricts these devices to sale by or on the order of a physician.
Edwards, Edwards Lifesciences, the stylized E logo, Edwards SAPIEN, Edwards SAPIEN 3, SAPIEN, and SAPIEN 3 are trademarks of Edwards Lifesciences Corporation. All other trademarks are the property of their respective owners.
© 2017 Edwards Lifesciences Corporation. All rights reserved. PP--US-2507 v1.0
Edwards Lifesciences One Edwards Way, Irvine CA 92614 USA edwards.com
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What People Say About Dr. Murali Dharan, MD
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He did a Valve repair in dec 2019 and I was a bit scared, but he took the time to make sure I fully understood the procedure. He was amazing. Thank you.
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J.Lopp – Apr 24, 2020
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Dr. Dharan and his Staff both in the Office Supporting him as well as the operating room are "Best in Class". A month ago I had a Mitral Valve repair. I had plenty of anxiety going into the procedure. Dr. Dharan as well as his office staff made me feel very confident of the process and outcome. I am currently in Cardiac Rehab and all has been great. The entire process was seamless for me. From pre-meetings with Dr. Dharan to the many insurance request I had for Tanya at the office in which was expedited at every request right away. Top notch Surgeon and top notch supporting team.
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1GC – Nov 09, 2019
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I had the Dx of Mitral Valve prolapse by echo-cardiogram. It was severe and I needed surgery. Dr. Dharan did an open-heart repair though a small incision in my right chest wall, between the ribs. I never experienced pain unless I coughed. I was out of the hospital in 5 days, and little more than two weeks later back to full functioning. Dr. Dharan was kind, amazingly skilled, explained everything fully to me and my family. I cannot recommend him for heart surgery too highly, he is talented and ethical in every way. Bob Nozik, MD
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3May 25, 2019
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Excellent surgeon! I had a mitral valve repair done recently, and Dr. Dharan was very patient in answering all my questions and putting me at ease. Prior to the procedure, he walked me through the process and gave me a timeline of what to expect during the recovery period. So far everything has gone exactly as Dr. Dharan had predicted. After the surgery, I often saw him in the ICU and Progressive Care checking up on his patients.
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2TLH in Moraga, CA – Oct 20, 2018
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I met with Dr. Dharan for a consultation for mitral valve regurgitation. The moment I met him, I knew this was the doctor for me. Dr. Dharan never talked over my head or down to me. His approach was caring and compassionate. The surgery went off without a hitch, with the condition being corrected. His surgical team were fantastic! The office staff is top notch and fun. Tanya is incredible at her job! My recommendation; Dr. Dharan, hands down!
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3Tracy, CA – Oct 16, 2018
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Dr. Dharan performed a perfect repair on my Mitral Valve August 8, 2108 using a mani minimally invasive procedure. Not only is he a great surgeon...he also has excellent interpersonal skills. He is a straight talker who cuts to the chase. I highly recommend Dr. Dharan. Leslie Reams
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3Leslie Reams in Walnut Creek, CA – Aug 17, 2018
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Dr. Dharan preformed a perfect repair on my Mitral Valve August 8, 2108 using a minimally invasive procedure. Not only is he a great surgeon...he also has excellent interpersonal skills. He is a straight talker who cuts to the chase. I highly recommend Dr. Dharan. Leslie Reams
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3Leslie Reams in Walnut Creek, CA – Aug 17, 2018
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Dr. Dharan is the most compassionate and empathetic physician I have had the pleasure to work with. His caring manner and clear explanations were extremely reassuring to me and my family as we had to decide between a stent or bypass procedure. I chose the bypass and am completely confident it was the right choice. Mine and my family's impression of Dr. Dharan was echoed by ALL of the nurses and staff at CCU in John Muir, who said I was lucky he was my cardiologist/surgeon.
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2Michael in Walnut Creek, CA – Jun 30, 2018
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Dr. Dharan performed an aortic valve replacement on me in May, 2018 at John Muir Cardiovascular Institute in Concord.. From my first visit with him, through my hospital stay and my follow-up appointment, he provided professional insight into my condition and confidence in the outcome. During my hospital stay, I also heard nothing but praise from ICU and PCU staff about his professional skills and personal relationships with patients and staff.
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4Ken Dixon in Concord, CA – Jun 26, 2018
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Dr. Dharan was recommended by my cardiologist, Dr. Parmodh Sidhu. We began with a personal interview and Dr. Dharan was extremely helpful and listened and questioned in a very comprehensive manner. He scheduled a series of tests and procedures prior to my actual mitral valve surgery to ensure full understanding of my condition and situation. My surgery was a complete success. I am grateful to have had Dr. Dharan as my surgeon and highly recommend him. Than you Dr. Dharan.
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3James Earle in San Ramon, CA – Jun 16, 2018
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Dr. Dharan was recommended by multiple sources; our primary care physician, pulmonologist & cardiologist. He is the Doctors, Doctor. After we con- sidered 3 surgeons, Dr. Dharan was the clear choice. He was on time for our appt., well versed about my husband’s case BEFORE he entered the room, was focused and engaged during our visit and showed outward concern for our concerns. Dr. Dharan performed both a lung biopsy and heart valve repair 5 wks. apart. Both 5-star experiences w/stellar results!
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31Diane Elliott in Lafayette, CA – May 28, 2018
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Dr. Dharan performed a Mitral Valve repair on me back in Nov 2015. I researched quite a few Dr's in my area and he came highly recommended but other Dr's including a friend of mine who happens to be an ER Dr. He was very polite and answered all my questions.
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5Troy S. in Concord, CA – Jan 19, 2017
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I don't recommend Dr.Dharan. He has a really poor bedside manner.
30 mins before my mom's surgery, he failed to draw her blood and poked through her vein due to lack of skills. He didn't apologize, instead, after my mom said it's hurting, he said: it isn't a big deal to be hurting for a minute. And he threatened her surgery might be cancelled.
My mom had a heart attack 2 months ago, and his rude demeanor negatively affected her emotional disposition. He demonstrated no empathy. Disappointing
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11Z. Jin in Concord, CA – Aug 30, 2016
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Dr. Dharan performed my open heart surgery in Feb of 2015. Honestly, more than a year later, I am feeling better than ever. He is an amazing surgeon.
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5Joe Noon in San Ramon, CA – Mar 17, 2016
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