Dr. Matthew Karpenko, DO

OncologyMaleAge 48

Oncology

Dr. Matthew Karpenko, DO is a Oncology Specialist in Orangeburg, SC. Dr. Karpenko has extensive experience in Pancreatic Neoplasms, Renal Neoplasms & Resection, and Blood Disorders. He is affiliated with medical facilities Grand Strand Medical Center and Guthrie Cortland Regional Medical Center. His office accepts new patients and telehealth appointments.

Dr. Matthew Karpenko, DO

The Mabry Center for Cancer Care

1161 Cook Rd Orangeburg, SC 29118 ()
Accepting new patients
Telehealth services available

Make an Appointment

(803) 395-4600

Telehealth available

Accepting new patients

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Hospital Highlight

Dr. Karpenko is affiliated with Grand Strand Medical Center Myrtle Beach, a highly rated hospital.

At a Glance

  • Explains Conditions Well
    Patients said this doctor explains conditions well. See reviews
  • Offers Telehealth
    This provider offers telehealth appointments. Call the office to schedule an appointment.
  • Practices at Top Hospital
    America's 250 Best Hospitals Award™ See hospitals

Experience and Background Checks

Experience
Background

Background Check

Healthgrades does not collect malpractice claims information for South Carolina
No disciplinary actions found for the years we collect data
No board actions found for the years we collect data
Learn more about background checks

Frequently Treated by Dr. Karpenko

Based on treatment records, we have identified the following as areas of care that Dr. Karpenko treats more often than their peers. If you are unsure whether Dr. Karpenko treats other conditions, please contact the office at (803) 395-4600.

Pancreatic Neoplasms

Pancreatic oncology focuses on the management and treatment of pancreatic cancer through chemotherapy, radiation, surgery, and targeted cancer therapy.Compare with other Pancreatic Neoplasms specialists.

Dr. Karpenko is experienced in the area of Pancreatic Neoplasms. See the graph below to learn more about his experience.

Based on claims data for 1 condition or procedure

Treatments
Dr. Karpenko
Similar Providers
Pancreatic Cancer
Normal
Frequency
High
Frequency
Very High
Frequency

Renal Neoplasms & Resection

Renal oncology focuses on the management and treatment of kidney cancer through surgery, immunotherapy, targeted therapy, radiation, and chemotherapy.Compare with other Renal Neoplasms & Resection specialists.

Treatments
Dr. Karpenko
Similar Providers
Kidney Cancer
Normal
Frequency
High
Frequency
Very High
Frequency

Blood Disorders

Blood disorders specialists diagnose and treat conditions that affect the blood's ability to function, including hemophilia, anemia, and sickle cell disease.Compare with other Blood Disorders specialists.

Dr. Karpenko is experienced in the area of Blood Disorders. See the graph below to learn more about his experience.

Based on claims data for 26 conditions and procedures

Treatments
Dr. Karpenko
Similar Providers
Anemia
Hypercoagulable State
Primary Hypercoagulable State (incl. Factor V Leiden Disease)
Coagulation Disorders (incl. Hemophilia)
Normal
Frequency
High
Frequency
Very High
Frequency
Hide other treatment areas

Check Dr. Karpenko's experience treating your condition or procedure

Dr. Karpenko's conditions and procedures:

  • Abdominal Pain
  • Acute Bronchitis
  • Acute Deep Vein Thrombosis (DVT)
  • Acute Lymphoid Leukemia
  • Acute Myeloid Leukemia
  • Acute Upper Respiratory Infection
  • Acute Venous Embolism Thrombosis
  • Adrenal Gland Cancer
  • All Headaches (incl. Migraine)
  • Anal and Rectal Cancer
  • Anal or Rectal Pain
  • Anemia
  • Anemia and Iron Deficiency Screening
  • Antiphospholipid Syndrome (APS)
  • Anxiety
  • Arthritis
  • Arthritis of the Elbow
  • Asthma
  • Asymptomatic Post-Menopausal Status
  • Atherosclerosis
  • Back Pain
  • Bedsores
  • Benign Chronic Pain Syndrome
  • Bile Duct Cancer
  • Bladder Cancer
  • Bladder Infection
  • Bleeding Disorders
  • Blood Disorders in Pregnancy
  • Blood in Urine (Hematuria)
  • Bone Cancer
  • Bone Density Scan
  • Bone Marrow Biopsy
  • Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
  • Brain Cancer
  • Breast Cancer
  • Bronchiectasis
  • Bronchitis
  • Calcium Metabolism Disorders
  • Cancer Screening
  • Cellulitis
  • Central Nervous System Lymphoma
  • Cervical Cancer
  • Chemotherapy
  • Chest Pain
  • Chordoma
  • Chronic Deep Vein Thrombosis (DVT)
  • Chronic Fatigue Syndrome
  • Chronic Lymphocytic Leukemia
  • Chronic Myeloid Leukemia (CML)
  • Chronic Neck Pain
  • Chronic Pain
  • Chronic Venous Embolism Thrombosis
  • Coagulation Disorders (incl. Hemophilia)
  • Coccygeal Pain
  • Colorectal Cancer
  • Constipation
  • COPD (Chronic Obstructive Pulmonary Disease)
  • Cough
  • CT Scan (Computed Tomography)
  • Deep Vein Thrombosis (DVT)
  • Dehydration
  • Diabetes Type 2
  • Diabetes With Renal Manifestations
  • Diabetic Polyneuropathy
  • Diarrhea
  • Diverticulitis, Intestinal
  • Diverticulosis, Intestinal
  • Dizziness
  • Ductal Carcinoma in Situ
  • Dyslipidemia
  • Dysphagia
  • Electrocardiogram (EKG)
  • Emphysema
  • Enlarged Prostate (BPH)
  • Erythropoietin Test
  • Esophageal Cancer
  • Familial Hypercholesterolemia
  • Fever
  • Fibromyalgia
  • Gallbladder and Biliary Tract Cancer
  • Gallbladder Cancer
  • Gastritis
  • Gastroesophageal Reflux Disease (GERD)
  • Gastroparesis
  • Gout
  • Gynecologic Cancer
  • Headache
  • Heart Disease
  • Hemophilia
  • Hernia
  • Herpes Zoster Without Complication
  • HIV (Human Immunodeficiency Virus)
  • Hives
  • Hodgkin's Disease
  • Hypercalcemia
  • Hypercoagulable State
  • Hyperkalemia
  • Hyperlipidemia
  • Hypertension
  • Hypokalemia
  • Hypothyroidism
  • Immune Thrombocytopenic Purpura (ITP)
  • Immunization Administration
  • Iron Metabolism Disorders
  • Irritable Bowel Syndrome
  • Joint Pain
  • Kidney Cancer
  • Lateral and Medial Epicondylitis (Tennis and Golf Elbow)
  • Leukocytosis
  • Limb Pain
  • Limb Swelling
  • Limb Swelling Caused by Fluid Overload
  • Lipid Disorders
  • Liver Cancer
  • Liver Damage from Alcohol
  • Lobular Carconima
  • Low Back Pain
  • Lung Cancer
  • Lung Neoplasms, Not Specified as Malignant
  • Lymphocytosis
  • Lymphoma, Large-Cell
  • Lymphosarcoma
  • Macroglobulinemia (incl. Waldenstrom's )
  • Magnesium Metabolism Disorders
  • Malaise and Fatigue
  • Male Breast Cancer
  • Malnutrition
  • Mantle Cell Lymphoma
  • Marginal Zone Lymphoma
  • Mastodynia
  • Maternal Anemia
  • Mediastinal Tumors, Malignant
  • Melanoma
  • Meningiomas
  • Menopausal and Postmenopausal Disorders
  • Menstrual Disorders (incl. Dysmenorrhea)
  • Migraine
  • Mineral Metabolism Disorders
  • Moles (Benign Skin Lesions)
  • Muscle Weakness
  • Mycosis Fungoides
  • Myelodysplastic Syndromes
  • Myeloma
  • Myeloproliferative Disorders
  • Nausea
  • Neuroendocrine Tumors
  • Neutropenia
  • Nodular Lymphoma
  • Non-Hodgkin's Lymphoma
  • Noninfectious Gastroenteritis and Colitis
  • Obesity
  • Oral Cancer
  • Oral Cancer Screening
  • Osteoarthritis
  • Osteoarthritis of Ankle and Foot
  • Osteoarthritis of Hand or Wrist
  • Osteoarthritis of Hip
  • Osteoarthritis of Hip and Thigh
  • Osteoarthritis of Knee
  • Osteoarthritis of Shoulder
  • Osteoarthritis of Spine
  • Osteopenia
  • Osteoporosis
  • Osteosarcoma
  • Ovarian Cancer
  • Overweight
  • Painful Urination (Dysuria)
  • Pancreatic Cancer
  • Pancytopenia
  • Paroxysmal Nocturnal Hemoglobinuria
  • Patellofemoral Pain Syndrome or Knee Pain
  • Pericardial Disease
  • Perimenopause
  • Peripheral T-Cell Lymphoma
  • Peritoneal Cancer
  • PET Scan
  • Phlebitis and Thrombophlebitis
  • Pleura Cancer
  • Pleural Cancer
  • Pneumonia
  • Polycythemia Rubra Vera
  • Polymyalgia Rheumatica (PMR)
  • Polyneuropathy
  • Primary Central Nervous System Lymphoma
  • Primary Hypercoagulable State (incl. Factor V Leiden Disease)
  • Prostate Cancer
  • Purpura
  • Qualitative Platelet Defects (incl. Glanzmann's Thrombasthenia)
  • Rash
  • Reticulosarcoma
  • Runner's Knee
  • Salivary Gland Stones and Inflammation
  • Sarcoidosis
  • Secondary Hypertension
  • Secondary Malignancies
  • Sexually Transmitted Diseases (STDs)
  • Shingles
  • Shortness of Breath
  • Skin Cancer
  • Skin Screenings
  • Sleep Apnea
  • Smoking Cessation Counseling
  • Soft Tissue Sarcoma
  • Squamous Cell Carcinoma
  • Stomach and Small Intestine Cancer
  • Stomach Cancer
  • Testicular Cancer
  • Thalassemia
  • Thoracentesis
  • Thrombocytosis
  • Thyroid Goiter
  • Tobacco Use Disorder
  • Tongue Cancer
  • Tremor
  • Urinary Stones
  • Urinary Tract Infection (UTI)
  • Uterine Cancer
  • Venous Embolism and Thrombosis
  • Vertigo
  • Viral Hepatitis
  • Vitamin B Deficiency
  • Vitamin B12 Deficiency
  • Vitamin D Deficiency
  • von Willebrand Disease
  • Wheezing

Insurance Check

Search for your insurance provider

Dr. Karpenko accepts most major insurance plans.

Dr. Karpenko has indicated that he accepts most major insurance carriers

Accepted insurance can change. Please double-check when making an appointment.

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Dr. Karpenko's Reviews

Likelihood to recommend Dr. Karpenko

4.2

Based on 33 ratings

5 Stars
78.78787878787878%
(26)
4 Stars
0%
(0)
3 Stars
0%
(0)
2 Stars
3.0303030303030303%
(1)
1 Star
18.181818181818183%
(6)
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Dr. Karpenko
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RecentHighestLowestMost Helpful
Reply
Very Good
I met Dr. Karpenko at Pinehurst, NC. He is very easy too speak with and was very upfront about my diagnosis. He did not speak down to me and talked to me like a person and explained my treatment plan. I would also say that he gave me options and when I felt the side effects of chemotherapy, he made the right dose adjustments to lessen the side effects. He is trustworthy and very responsive to my needs. Highly recommended.
What went well
  • Wait times
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
1 person found this helpful
Helpful
M.M. – May 01, 2022
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Reply
Dr. Karpenko saved my life when I was diagnosed with a mass that surrounded my trachea. He immediately brought the team together and started chemo and radiation which was a life threatening situation on a Holliday weekend (NYE). Without a doubt I would highly recommend his expertise as an Oncologist
3 people found this helpful
Helpful
MK – Jan 14, 2022
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Reply
I am new to the area and needed to establish care with a oncologist/hematologist. I contacted First Health Cancer and was given an appt with Dr. K. I had a 10 minute visit with the doctor and my insurance was charged $540! Of which, I owe $300! Since then I have had to contact him and I find he doesn’t listen to my concerns and he doesn’t reply to my questions through My Chart. I was having pain in my left hip and asked about a referral for a MRI. As a breast cancer survivor, pain as I was having was a concern. His nurse contacted me and I was told the doctor said I would need to go to a primary care that he wasn’t treating me for hip pain. From my previous experience with my Indianapolis oncologist he provided total body care. I was astounded and requested to change doctors, but was told by his nurse that I am not able to change to another doctor in the practice. I was told I would have to go elsewhere. So, no I would not recommend this doctor to anyone!
What went well
  • Office environment
  • Wait times
What could be improved
  • Didn't listen or answer questions
  • Didn't trust the provider's decisions
Helpful
Lisa Johnson – Dec 31, 2021
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Reply
Met him in NC. Explains things well that I can understand. Communicates well, kind, and compassionate. Available to answer questions- has even called me to check in. Highly recommended.
What went well
  • Appointment scheduling
  • Office environment
  • Staff friendliness
  • Wait times
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
4 people found this helpful
Helpful
T.K. – Jul 18, 2021
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Reply
I miss and love Dr Karpenko. He was my cancer doctor at the Auburn, NY H&O. He really cares about his patients. Wish he was still in Auburn. He is really the best.!!!!!!!!
What went well
  • Appointment scheduling
  • Office environment
  • Staff friendliness
  • Wait times
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
4 people found this helpful
Helpful
Angie Martino-Gregory – Jul 15, 2021
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Reply
Truly cares. Outstanding staff. 100% confident in his care. Great communicator. Overall exceptional experience!
What went well
  • Appointment scheduling
  • Office environment
  • Staff friendliness
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
4 people found this helpful
Helpful
Patient – May 08, 2020
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Reply
He is the best
What went well
  • Trusted the provider's decisions
What could be improved
No results
6 people found this helpful
Helpful
Diane sutton – Aug 02, 2019
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Reply
Seemed like a friendly person, but doesn't appear to like to answer questions--gets a little touchy. Could be better at explaining. Could have avoided a lot of heart ache if had been better explained. Had a quick but important question before a procedure; most of my doctors would speak to me on the phone, but Dr. Karpenko relayed word that I would have to come in for another office visit.
What went well
  • Office environment
  • Staff friendliness
  • Wait times
What could be improved
  • Didn't listen or answer questions
  • Didn't explain conditions well
2 people found this helpful
Helpful
Cortland, NY – Jun 10, 2017
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Reply
Dr.Karpenko is hands down the best doctor I have ever had. He is so dedicated to helping his patients. He is compassionate, empathetic, and so incredibly smart. He explains everything perfectly and listens to any and all questions and concerns. I would trust Dr. Karpenko with my life. So appreciative of him and his efforts.
What went well
  • Appointment scheduling
  • Office environment
  • Wait times
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
9 people found this helpful
Helpful
May 16, 2017
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Reply
Dr. Karpenko is on top of his game : Thorough and focused. Took his time and explained everything in detail. I can unequivocally recommend him to others. A good listener and communicator.
What went well
  • Appointment scheduling
  • Office environment
  • Staff friendliness
  • Wait times
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
11 people found this helpful
Helpful
Tom Allport in Cortland , NY – Feb 12, 2017
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Reply
Doctor Karpenko treated my mother in Conway SC in 2014 . He is the best all around human ever made and the fact that he chose to help the helpless and sometimes the hopeless is a blessing .I would always recamind him .He understands the value of life.
11 people found this helpful
Helpful
Angela Mcdonald in Conway, SC – Jan 05, 2017
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Reply
Dr. Karpenko took me from stage 4 to non-detectable cancer. I value his knowledge and treatment methods. He is a very caring and concerned doctor. I have since moved out of state, but am planning to return in the near future. I will seek Dr. Karpenko out for future ongoing care.
What went well
  • Appointment scheduling
  • Office environment
  • Staff friendliness
  • Wait times
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
11 people found this helpful
Helpful
Bruce Rowe in Lawrenceville, GA – Jul 27, 2016
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About Me

Care Philosophy

Dr. Karpenko has joined Pinehurst Medical Hematology/ Oncology.  A Native from Rochester, NY, Dr. Karpenko completed his Hematology/Oncology Fellowship...Read more

Specialties

  • Oncology
  • Hematology
  • Internal Medicine

Board Certifications

  • Hematology
  • Medical Oncology

Education

2005
Ohio State University
Fellowship Hospital
2005
2005 Chief Resident
Residency Hospital
2005
United Health Services Hospitals
Residency Hospital
2002
United Health Services
Internship Hospital
1996
Syracuse University
Undergraduate School
,

Awards

Frequently Asked Questions

Does Dr. Matthew Karpenko, DO offer telehealth services?

Dr. Karpenko has indicated that they offer telehealth. Contact the office to check for eligibility for your needs.

Is Dr. Matthew Karpenko, DO accepting new patients?

Dr. Matthew Karpenko, DO generally accepts new patients on Healthgrades. You can see Dr. Karpenko's profile to make an appointment.

Does Dr. Matthew Karpenko, DO accept my insurance?

Use the Healthgrades insurance check to verify if Dr. Karpenko accepts your insurance.

What are Dr. Matthew Karpenko, DO's top areas of care?

Dr. Karpenko frequently treats Pancreatic Neoplasms, Renal Neoplasms & Resection, and Blood Disorders. See all practice areas where Dr. Karpenko specializes.

Where is Dr. Matthew Karpenko, DO's office located?

Dr. Karpenko's office is located at 1161 Cook Rd, Orangeburg, SC 29118. Find other locations and directions on Healthgrades.

How can I make an appointment with Dr. Matthew Karpenko, DO?

Find contact information here to make an appointment.

Locations

Practice

The Mabry Center for Cancer Care1161 Cook Rd Orangeburg, SC 29118
1
Peninsula Regional Medical Center100 E Carroll St Salisbury, MD 21801
2

Affiliated Hospitals

Dr. Karpenko is affiliated with the following hospitals. Select a hospital below to learn more.

Learn more about how Healthgrades measuresHospital Quality.

Grand Strand Medical Center

Myrtle Beach, SC

72% Patients that would definitely recommend, 2% higher than the national average

22 Awards Received

Award Highlight: Patient Safety Excellence Award™ (2022)

Guthrie Cortland Regional Medical Center

Cortland, NY

56% Patients that would definitely recommend, 14% lower than the national average