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My current research program studies the associations between environmental arsenic exposure and neural tube defects, a particular group of birth defects that involve the developing brain and spinal cord. The study of neural tube defects provides a unique opportunity to learn about the complex interaction between environment, genes, and nutrition, and their combined effects on the developing nervous system. The long-range goals of my research program are 1) to develop novel screening strategies, appropriate for use in resource poor settings, to identify populations at high risk of neural tube defects, 2) to direct the development of more effective, mechanism-based preventive interventions for neural tube defects and 3) to test whether the biological pathways discovered linking nutrition, environmental hazards and neural tube defect risk are also involved in less severe neurodevelopmental disorders in children. Currently, this NIH-supported research takes place among infants and children in Bangladesh, a country grappling with the largest arsenic epidemic in world history.
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Learn about Dr. Mazumdar
I observed that doctors often play an important role in a family's life, often at a time that is particularly stressful for the family. I thought that as a doctor, I could use my own particular skills – my knowledge of science – to be a resource for families during difficult times.