Dr. Luis Zayas, MD

NeurologyMaleAge 46

Dr. Luis Zayas, MD is a Neurology Specialist in Knoxville, TN. Dr. Zayas has more experience with Epilepsy than other specialists in his area. He is affiliated with medical facilities Blessing Hospital and University of Tennessee Medical Center. He is accepting new patients and has indicated that he accepts telehealth appointments. Be sure to call ahead with Dr. Zayas to book an appointment.

Dr. Zayas

Cole Neuroscience Center

1975 Town Center Blvd # 203 Knoxville, TN 37922
Accepting new patients
Telehealth services available

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Hospital Highlight

Dr. Zayas is affiliated with University of Tennessee Medical Center Knoxville, a highly rated hospital.

At a Glance

  • Explains Conditions Well
    Patients said this doctor explains conditions well. See reviews
  • Offers Telehealth
    This provider offers telehealth appointments. Call the office to schedule an appointment.
  • Practices at Top Hospital
    America's 250 Best Hospitals Award™ See hospitals

Experience and Background Checks


Background Check

No malpractice claims found for Tennessee
No disciplinary actions found for the years we collect data
No board actions found for the years we collect data
Learn more about background checks

Frequently Treated by Dr. Zayas

Based on treatment records, we have identified the following as areas of care that Dr. Zayas treats more often than their peers. If you are unsure whether Dr. Zayas treats other conditions, please contact the office at (865) 909-4030.


Epilepsy specialists diagnose and treat spectrum of brain disorders that cause seizures due to an interruption of normal nerve activity in the brain.Compare with other Epilepsy specialists.

Dr. Zayas is experienced in the area of Epilepsy. See the graph below to learn more about his experience.

Based on claims data for 3 conditions and procedures

Dr. Zayas
Similar Providers
Essential Tremor
Seizure Disorders
EEG (Electroencephalogram)
Very High

Check Dr. Zayas' experience treating your condition or procedure

Dr. Zayas' conditions and procedures:

  • Asterixis (Flapping Tremor)
  • Ataxia
  • Ataxia, Hereditary, Autosomal Dominant
  • Autonomic Disorders
  • Benign Essential Tremor
  • Brainstem Auditory Evoked Response Test
  • Cerebellar Ataxia
  • Cerebrovascular Disease
  • Chorea (Excluding Huntington's Chorea)
  • Cognitive Function Testing
  • Compound Muscle Action Potential (CMAP) Scan
  • Confusion
  • Corticobasal Degeneration
  • Deep Brain Stimulation Evaluation
  • Dementia
  • Dementia Evaluation
  • Dementia or Depression Screening
  • Difficulty With Walking
  • Dystonia
  • EEG (Electroencephalogram)
  • Epilepsy
  • Essential Tremor
  • Evaluation and Treatment of Sleep Disorders
  • Evaluation for Stereotactic and Functional Neurosurgery
  • Evoked Potential Test
  • Friedreich's Ataxia
  • Functional Movement Screening
  • Gait Abnormality
  • Grip and-or Muscle Group Pull Test
  • Head CT Scan
  • Home Sleep Study
  • Huntington's Disease
  • ImPACT Testing
  • Lewy Body Dementia
  • Loss of Taste
  • Medication-Induced Postural Tremor
  • Memory Evaluation
  • Nerve Block, Somatic
  • Non-Cosmetic Chemodenervation
  • Normal Pressure Hydrocephalus
  • Orthostatic Tremor
  • Parkinson's Disease
  • Parkinsonism
  • Peripheral Neuropathy Testing
  • Progressive Supranuclear Palsy (PSP)
  • Quantitative Sensory Test (QST)
  • Restless Leg Syndrome
  • Seizure Disorders
  • Sleep Study
  • Spastic Gait
  • Spasticity - Mental Retardation
  • Spinocerebellar Ataxia
  • Stroke
  • Sudoscan
  • Syncope
  • TCD Bubble Test
  • Tic Disorders
  • Torticollis
  • Tourette's Syndrome
  • Transient Ischemic Attack (TIA)
  • Tremor
  • Tremor Hereditary Essential, 1
  • Tremor Hereditary Essential, 2
  • Vascular Disease
  • Vitamin B Deficiency
  • Wada Test

Insurance Check

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Dr. Zayas accepts

Accepted insurance can change. Please double-check when making an appointment.

(865) 909-4030

Dr. Zayas accepts the following insurance:

Aetna HMO
Choice Plus POS II
Blue Access Choice (St Louis) (Select Network)-IL
National (BlueCard Basic) PPO
National (BlueCard) PPO
Anthem Blue Cross Blue Shield
Anthem Blue Cross Blue Shield PPO
Blue Preferred Plus POS
Blue Cross Blue Shield
Blue Card PPO
CareFirst Blue Cross Blue Shield
HealthyBlue 2.0
HealthyBlue Advantage
Cigna HMO
Cigna PPO
Open Access Plus
HAP Insurance
Health Alliance PPO
Choice Care PPO
Preferred PPO
MultiPlan PPO

Dr. Zayas' Reviews

Likelihood to recommend Dr. Zayas


Based on 3 ratings

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4 Stars
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Dr. Zayas
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What went well
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What could be improved
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RecentHighestLowestMost Helpful
Absolutely terrific at explaining my neurological problems and possible treatments.
What went well
  • Staff friendliness
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
Matthew C Leveque – Jul 02, 2021
Was very sorry to see him leave Peoria! He was a very caring and knowledgeable Doctor! Wish he was still here!
What went well
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
1 person found this helpful
Linda Gardiner – Apr 03, 2021
Excellent physician. I have received really great care from DR Zayas. The staff is excellent. He really takes enough time during his initial evaluation.
What went well
  • Appointment scheduling
  • Office environment
  • Staff friendliness
  • Wait times
  • Appointment wasn't rushed
  • Listened & answered questions
  • Explained conditions well
  • Trusted the provider's decisions
What could be improved
No results
4 people found this helpful
Bertha in Quincy, IL – Aug 26, 2017

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About Me


Dr. Zayas grew up in Trujillo Alto, a small town in the Puerto Rican countryside.

After completing his bachelor's degree in physical therapy,...
Read more


  • Neurology
  • Neurocritical Care
  • Neurological Movement Disorders
  • Neurological Physical Therapy

Board Certifications

  • Epilepsy
  • Internal Medicine
  • Neurology


University Of Nebraska Medical Center-Omaha
Fellowship Hospital
Cleveland Clinic, Cleveland, Oh
Fellowship Hospital
Cooper University Hosp-UMDNJ
Residency Hospital
St Barnabas Hosp Bronx
Residency Hospital
University of Puerto Rico, Medical Science Center
Undergraduate School


  • English
  • Spanish


Frequently Asked Questions

Does Dr. Luis Zayas, MD offer telehealth services?

Dr. Zayas has indicated that they offer telehealth. Contact the office to check for eligibility for your needs.

Is Dr. Luis Zayas, MD accepting new patients?

Dr. Luis Zayas, MD generally accepts new patients on Healthgrades. You can see Dr. Zayas' profile to make an appointment.

Does Dr. Luis Zayas, MD accept my insurance?

Use the Healthgrades insurance check to verify if Dr. Zayas accepts your insurance.

What are Dr. Luis Zayas, MD's top areas of care?

Dr. Zayas frequently treats Epilepsy. See all practice areas where Dr. Zayas specializes.

Where is Dr. Luis Zayas, MD's office located?

Dr. Zayas' office is located at 1975 Town Center Blvd # 203, Knoxville, TN 37922. Find other locations and directions on Healthgrades.

What languages does Dr. Luis Zayas, MD speak?

Dr. Zayas speaks Spanish and English. View profile to see all.

How can I make an appointment with Dr. Luis Zayas, MD?

Find contact information here to make an appointment.


Cole Neuroscience Center

University Neurology Cole Neuroscience Center1975 Town Center Blvd # 203 Knoxville, TN 37922
  • Call
  • Fax
  • Hours
    • Mon: 8:00am - 5:00pm
    • Tue: 8:00am - 5:00pm
    • Wed: 8:00am - 5:00pm
    • Thu: 8:00am - 5:00pm
    • Fri: 8:00am - 5:00pm
    • Sat: closed
    • Sun: closed
  • Directions

Affiliated Hospitals

Dr. Zayas is affiliated with the following hospitals. Select a hospital below to learn more.

Learn more about how Healthgrades measuresHospital Quality.

Blessing Hospital

Quincy, IL

73% Patient Experience Rating, 4% higher than the national average

1 Award Received

University of Tennessee Medical Center

Knoxville, TN

75% Patient Experience Rating, 6% higher than the national average

12 Awards Received

Award Highlight: Patient Safety Excellence Award™ (2021)