Dr. Joseph Mignone, MD

Dr. Joseph Mignone, MD

Medical OncologyMaleAge 49

Accepting new patients

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(904) 427-1050

Dr. Joseph Mignone, MD is a Medical Oncology Specialist in Jacksonville, FL. Dr. Mignone has more experience with Blood Disorders than other specialists in his area. He is affiliated with medical facilities such as Memorial Hospital Jacksonville and Orange Park Medical Center. He is accepting new patients. Be sure to call ahead with Dr. Mignone to book an appointment.


21st Century Oncology of Jacksonville

New Patient?
(904) 427-1050
21st Century Oncology of Jacksonville7751 Baymeadows Rd E Ste 205 Jacksonville, FL 32256

UF Health

New Patient?
(904) 427-1050
UF Health15255 Max Leggett Pkwy Ste 120 Jacksonville, FL 32218

Hospital Highlight

Dr. Mignone is affiliated with Memorial Hospital Jacksonville Jacksonville, a highly rated hospital.

At a Glance

  • Explains Conditions Well Patients said this doctor explains conditions well. See reviews
  • Practices at Top Hospital America's 250 Best Hospitals Award™ See hospitals
  • Hospital Satisfaction Patients said they were highly satisfied at this doctor's hospital. See hospitals

More Oncology Specialists at 21st Century Oncology of Jacksonville

Dr. Mignone's Reviews

Likelihood to recommend Dr. Mignone


Based on 16 ratings

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What went well
  • Office environment (13)
  • Staff friendliness (13)
  • Appointment scheduling (12)
What could be improved
  • Appointment was rushed (3)
  • Didn't explain conditions well (3)
  • Didn't listen or answer questions (3)
RecentHighestLowestMost Helpful
Reply Flag
I got six rounds of chemotherapy, thank God am doing better
What went well
No results
What could be improved
No results
Ibrahima – Feb 05, 2020
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Dr. Mignone is amazing! You will not find a better doctor with a good heart. What more can I say but he saved my life. There are not enough stars I can put on here. I cannot say enough good things about him and his staff. All wonderful people.
What went well
No results
What could be improved
No results
9 people found this helpful
GypsyMermaid in Atlantic Beach florida – Jul 02, 2016
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Experience and Background Checks


Background Check

No malpractice claims found for Florida
No disciplinary actions found for the years we collect data
No board actions found for the years we collect data
Learn more about background checks

Frequently Treated by Dr. Mignone

Based on treatment records, we have identified the following as areas of care that Dr. Mignone treats more often than their peers. If you are unsure whether Dr. Mignone treats other conditions, please contact the office at (904) 427-1050.

Blood Disorders

Blood disorders specialists diagnose and treat conditions that affect the blood's ability to function, including hemophilia, anemia, and sickle cell disease.Compare with other Blood Disorders specialists.

Dr. Mignone is experienced in the area of Blood Disorders. See the graph below to learn more about his experience.

Based on claims data for 25 conditions and procedures

Dr. Mignone
Similar Providers
Bleeding Disorders
Coagulation Disorders (incl. Hemophilia)
Very High

Check Dr. Mignone's experience treating your condition or procedure

Dr. Mignone's conditions and procedures:

  • Acute Leukemia
  • Acute Lymphoid Leukemia
  • Acute Myeloid Leukemia
  • Anemia
  • Antiphospholipid Syndrome (APS)
  • Aortic Embolism and Thrombosis
  • Bleeding Disorders
  • Blood Disorders in Pregnancy
  • Bone Marrow Aspiration
  • Bone Marrow Biopsy
  • Cancer Treatment
  • Central Nervous System Lymphoma
  • Chronic Lymphocytic Leukemia
  • Chronic Myeloid Leukemia (CML)
  • Coagulation Disorders (incl. Hemophilia)
  • Deep Vein Thrombosis (DVT)
  • Hemophilia
  • Hemophilia A
  • Hypercoagulable State
  • Immune Thrombocytopenic Purpura (ITP)
  • Leukocytosis
  • Lymphocytosis
  • Lymphoma, Large Cell, Anaplastic
  • Maternal Anemia
  • Myelodysplastic Syndromes
  • Myeloma
  • Myeloproliferative Disorders
  • Neutropenia
  • Non-Hodgkin's Lymphoma
  • Pancytopenia
  • Plasmapheresis
  • Polycythemia Rubra Vera
  • Primary Central Nervous System Lymphoma
  • Primary Hypercoagulable State (incl. Factor V Leiden Disease)
  • Purpura
  • Sickle Cell Disease
  • Thalassemia
  • Thoracentesis
  • Thrombocytosis
  • Venous Embolism and Thrombosis
  • Vitamin B Deficiency
  • Vitamin B12 Deficiency
  • von Willebrand Disease

Insurance Check

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Dr. Mignone accepts

Accepted insurance can change. Please double-check when making an appointment.

(904) 427-1050

Dr. Mignone accepts the following insurance:

Aetna HMO
Choice Plus POS II
National (BlueCard) PPO
Blue Cross Blue Shield
Blue Card PPO
Blue Cross Blue Shield of Florida
Blue Care HMO
Blue Select
BlueDental Choice
Blue Cross Blue Shield of Georgia
Blue Open Access POS
CareFirst Blue Cross Blue Shield
HealthyBlue 2.0
HealthyBlue Advantage
Cigna HMO
Cigna PPO
Open Access Plus
First Health (Coventry Health Care)
First Health (Coventry Health Care) PPO
Choice Care PPO
Preferred PPO
Select HMO
MultiPlan PPO
PHCS Network PPO

About Me

Care Philosophy

21st Century Oncology is the premier provider of cancer care services across multiple modalities, the largest radiation oncology provider and one of the...Read more


Dr. Mignone was the recipient of Castle Connolly's Top Doctors Award in 2007 to the present and named US New and World Report Top Doctor. In addition,...Read more


  • Medical Oncology
  • Hematology

Board Certifications

  • Hospice Care and Palliative Medicine


University Of Florida
Fellowship Hospital
University Of Florida
Residency Hospital


Frequently Asked Questions

How can I make an appointment with Dr. Joseph Mignone, MD?

Call (904) 427-1050 to make an appointment as a new patient. Click here for more information.

Is Dr. Joseph Mignone, MD accepting new patients?

Dr. Joseph Mignone, MD generally accepts new patients on Healthgrades. You can see Dr. Mignone's profile to make an appointment.

Does Dr. Joseph Mignone, MD accept my insurance?

Use the Healthgrades insurance check to verify if Dr. Mignone accepts your insurance.

What are Dr. Joseph Mignone, MD's top areas of care?

Dr. Mignone frequently treats Blood Disorders. See all practice areas where Dr. Mignone specializes.

Where is Dr. Joseph Mignone, MD's office located?

Dr. Mignone's office is located at 7751 Baymeadows Rd E Ste 205, Jacksonville, FL 32256. Find other locations and directions on Healthgrades.

Does Dr. Joseph Mignone, MD offer telehealth services?

Dr. Mignone has not yet indicated whether they offer telehealth services. Please contact the office to check for availability/eligibility.

Affiliated Hospitals

Dr. Mignone is affiliated with the following hospitals. Select a hospital below to learn more.

Learn more about how Healthgrades measuresHospital Quality.

Memorial Hospital Jacksonville

Jacksonville, FL

65% Patient Experience Rating, 4% lower than the national average

6 Awards Received

Award Highlight: Patient Safety Excellence Award™ (2018)

Orange Park Medical Center

Orange Park, FL

62% Patient Experience Rating, 7% lower than the national average

12 Awards Received

Award Highlight: America's 250 Best Hospitals Award™ (2020)

Ascension St. Vincent's Riverside Hospital

Jacksonville, FL

72% Patient Experience Rating, 3% higher than the national average

1 Award Received

Award Highlight: Patient Safety Excellence Award™ (2020)

Baptist Medical Center Jacksonville

Jacksonville, FL

75% Patient Experience Rating, 6% higher than the national average

1 Award Received

Uf Health Jacksonville

Jacksonville, FL

71% Patient Experience Rating, 2% higher than the national average

9 Awards Received

Award Highlight: America's 250 Best Hospitals Award™ (2019)