Dr. John DeSantis, DO

Dr. John DeSantis, DO

Orthopedic Surgery  ·  
Male  ·  
Age 65
Dr. John DeSantis, DO is an orthopedic surgery specialist in Rancho Mirage, CA and has been practicing for 30 years. He graduated from Michigan State University / College Of Osteopathic Medicine in 1980 and specializes in orthopedic surgery, joint replacement orthopedic surgery, and more.Read his story

39000 Bob Hope Dr

Rancho Mirage, CA 92270

Contact Information

(760) 568-2684

Insurance Accepted

  • Accepts most major Health Plans. Please contact our office for details.

*Please verify this information when scheduling an appointment.

Learn about Dr. DeSantis

Be confident in your decisions by checking out your provider's top areas of care, education, patient reviews and more. Learn about finding the right doctor for you.

Top Care Areas

See how frequently Dr. DeSantis performs your care needs compared to other doctors.

Knee Replacement
very high
more than 93% of peers
Hip Replacement
more than 81% of peers
Arthritis of the Elbow
more than 5% of peers

Dr. DeSantis's percentages are based on the rate of treatment compared to peers nationwide from insurance data. Learn more info about our data and this Top Care Areas component.

Dr. DeSantis' bio

This content was provided by Dr. DeSantis "John G. DeSantis, D. O., is a board certified fellowship-trained orthopedic surgeon specializing in total hip and total knee reconstruction. A native of Michigan, Dr. DeSantis moved to Southern California to join Desert Orthopedic Center in 2008. Prior to moving to Rancho Mirage, Dr. DeSantis practiced in Michigan where he had established the Knee and Orthopedic Center in 1988 after completion of his fellowship in Florida. Dr. DeSantis has successfully performed thousands of hip and knee surgeries including arthroscopic knee surgery, total hip replacement and hip resurfacing, total knee and partial knee replacement, custom knee replacement, revision hip and revision knee replacement, bilateral knee replacement and combined hip and knee replacement surgery. Dr. DeSantis performs hip surgeries through the "bikini incision" anterior approach. The biggest advantage for his patients is that this allows immediate freedom in their hip range of motion and early return to their desired activities. He prefers this approach as patients are not required to follow traditional hip precautions which limit hip flexion and range of motion postoperatively. Dr. DeSantis graduated from Michigan State University College of Osteopathic Medicine and completed an orthopedic residency at Detroit Osteopathic/Bi County Community Hospital in Michigan. He is a Diplomat of the National Board of Examiners and has served as an oral examiner for the AOA Orthopedic Certification Examination. He is a member of the American Medical Association, the American Osteopathic Academy of Orthopedics, American Osteopathic Association, the American Osteopathic Academy of Sports Medicine and the American Association of Hip and Knee Surgeons."
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Care Philosophy

This content was provided by Dr. DeSantis ""The most rewarding part of hip and knee reconstruction is hearing from patients how happy they are that they can get back to activities they once enjoyed""

5  Specialties

  • Orthopedic Surgery
  • Bone & Joint Non-Surgical Orthopedics
  • Joint Replacement & Reconstruction Orthopedics
  • Joint Replacement Orthopedic Surgery
  • Non-Surgical Orthopedics

1  Board Certifications

  • Orthopedic Surgery
    Accredited by: American Osteopathic Board of Orthopedic Surgery*

11  Conditions Treated

  • Ankle and Foot Instability or Derangement
  • Arthritis of the Elbow
  • Ataxia
  • Bone Cancer
  • Broken Neck
  • Hip Pain
  • Knee Pain
  • Lumbar Spine Fracture
  • Morton's Neuroma
  • Nerve Root Injury and Plexus Disorders (incl. Pinched Nerve)
  • Osteoarthritis of Hands

5  Procedures

Background Check

0 Malpractice Claims

No malpractice history found for California.

0 Sanctions

No sanctions history found for the years that Healthgrades collects data.

0 Board Actions

No board actions found for the years that Healthgrades collects data.


  • Central Michigan University
    Undergraduate School | Graduated 1977
  • Michigan State University / College Of Osteopathic Medicine
    Medical School | Graduated 1980
  • Detroit Osteopath/Bicounty Hosps
    Internship Hospital | Completed 1981
  • Detroit Osteopathic Hospital
    Residency Hospital | Completed 1986
  • The Florida Knee Center
    Fellowship Hospital | Completed 1988

Awards & Recognition

Awards & Honors
  • Healthgrades Honor Roll
Media & Publications

Dr. DeSantis has no media or publications listed.

Languages Spoken

  • English

Memberships & Professional Affiliations

  • California Orthopedic Association, Member

Dr. DeSantis' Reviews

Likelihood of recommending Dr. DeSantis to family and friends
67 total reviews (41 have comments)

Likelihood to Recommend (67)

  • 5
  • 4
  • 3
  • 2
  • 1

Dr. DeSantis' Performance

  • Trustworthiness

  • Explains condition(s) well

  • Answers questions

  • Time well spent


Office & Staff Performance

  • Scheduling

  • Office environment

  • Staff friendliness

  • Average wait time

    10 to 15 minutes

Patient Comments (41)

Wonderful man and surgeon ??. I had a hip replacement Oct. 4 last year and am walking ?? normal and painfree now in March. Highly recommend him. Hedy Hartmann, Kelowna, BC
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Both of my hips were causing me great discomfort and I would have been in a wheelchair without Dr DeSantis' hip replacement surgery. Both hips needed replacing so he suggested doing both at the same time. We both agreed and afterwards I was up and able to walk the next day. My recovery went...more
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I had bi-lateral knee replacement in July 2017 by Dr. DeSantis. I had been having gel injections for 2 years and needed both knees replaced. Thank goodness he was willing to do both at one time. I certainly did not want to go through surgery twice. He was professional and to the point. I am...more
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Excellent Doctor and staff. TKR revision(he had to fix another surgery, from another state). From start to finish, I was heard, tested and given options. He is skilled, confident and caring. Thank you Dr. You have helped me reclaim my life! Start to finish, no complaints from me! Highly...more
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I have been seen by Dr. DeSantis since April of 2017, for a work related knee injury. Dr. Desantis has been, by far, one of very best doctors I have ever dealt with. He is extremely experienced in his field, and his contact with patients is outstanding. He carefully explains options and his...more
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