Dr. Jeffrey Perlman, MD

Dr. Jeffrey Perlman, MD

Endocrinology, Diabetes & Metabolism  ·  
Male  ·  
Age 65
Dr. Jeffrey Perlman, MD is an endocrinology, diabetes & metabolism specialist in Plano, TX and has been practicing for 26 years. He graduated from University Of Pittsburgh School Of Medicine in 1982 and specializes in endocrinology, diabetes & metabolism.

6124 W Parker Rd Ste 332

Plano, TX 75093

Contact Information

(972) 981-7812

Insurance Accepted

  • Accepts most major Health Plans. Please contact our office for details.
  • Blue Cross Blue Shield
  • Cigna
  • Galaxy Health Network
  • HealthSmart
  • Humana
  • MultiPlan
  • Texas True Choice
  • UnitedHealthCare
  • 2 More

*Please verify this information when scheduling an appointment.

Learn about Dr. Perlman

Be confident in your decisions by checking out your provider's top areas of care, education, patient reviews and more. Learn about finding the right doctor for you.

Top Care Areas

See how frequently Dr. Perlman performs your care needs compared to other doctors.

Diabetes Counseling
very high
more than 98% of peers
Thyroid Disease
very high
more than 95% of peers
very high
more than 93% of peers

Dr. Perlman's percentages are based on the rate of treatment compared to peers nationwide from insurance data. Learn more info about our data and this Top Care Areas component.

Care Philosophy

This content was provided by Dr. Perlman "We are an Endocrinology private practice specializing in diabetes, osteoporosis, and thyroid, parathyroid, lipid (cholesterol and triglycerides), pituitary, and adrenal disorders. We take the time to treat our patients right."

1  Specialties

  • Endocrinology, Diabetes & Metabolism

2  Board Certifications

  • Diabetes, Metabolism & Endocrinology
    Accredited by: American Board of Internal Medicine*
  • Internal Medicine
    Accredited by: American Board of Internal Medicine*

55  Conditions Treated

Read Less

7  Procedures

  • Bone Density Scan
  • Continuous Glucose Monitoring
  • Diabetes Counseling
  • Insulin Pump Therapy
  • Thyroid Fine Needle Aspiration Biopsy
  • Thyroid Nodule Evaluation
  • Ultrasound, Thyroid

Background Check

0 Malpractice Claims

No malpractice history found for Texas.

0 Sanctions

No sanctions history found for the years that Healthgrades collects data.

0 Board Actions

No board actions found for the years that Healthgrades collects data.


  • Johns Hopkins University / School Of Medicine
    Undergraduate School | Graduated 1976
  • University Of Pittsburgh School Of Medicine
    Medical School | Graduated 1982
  • Mt. Sinai Medical Center
    Internship Hospital | Completed 1983
  • Mt. Sinai Medical Center
    Residency Hospital | Completed 1985
  • New York-Presbyterian Hospital/Memorial Sloan Kettering Cancer Center
    Fellowship Hospital | Completed 1992
  • New York-Presbyterian Hospital/Weill Cornell Medical Center
    Fellowship Hospital | Completed 1995

Awards & Recognition

Awards & Honors
  • Healthgrades Honor Roll
  • Alpha Omega Alpha Medical Student Honor Society, 1981
  • Merck Senior Fellow Award, 1995
  • First Place Knoll Thyroid Research Award, 1995
  • Fellow, American College of Endocrinology, 1995
  • NIH Physician Scientist Award, 1992
  • AMA Physician Recognition Award with Commendation, 2012
  • International Society for Clinical Densitometry Certified Clinical Densitometrist, 2009
Media & Publications
  • Endocrinology, Third Edition, edited by Leslie J. deGroot Principles of Hormone Action, Second Messenger Signaling Pathways: Phosphatidylinositol and Calcium, 1995
  • Laakkonen LJ, Guarnieri F, Perlman JH, Gershengorn MC, Osman R: A refined model of the thyrotrophin-releasing hormone (TRH) receptor binding pocket. Novel mixed mode Monte Carlo/stochastic dynamics simulations of the complex between TRH and TRH receptor. Biochemistry 1996 Jun 18; 35(24):7651-63,
  • Perlman JH, Colson AO, Jain R, Czyzewski B, Cohen LA, Osman R, Gershengorn MC: Role of the extracellular loops of the thyrotrophin-releasing hormone receptor: evidence for an initial interaction with thyrotrophin-releasing hormone. Biochemistry 1997 Dec 16; 36(50):15670-6,
  • Perlman JH, Gershengorn MC: Thyrotrophin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium. Endocrinology 1991 Nov; 129(5):2679-86,
  • Perlman JH, Thaw CN, Laakkonen L, Bowers CY, Osman R, Gershengorn MC: Hydrogen bonding interactions of thyrotrophin-releasing hormone (TRH) with transmembrane tyrosine 106 of the TRH receptor. J Biol Chem 1994; 269(3):1610-3,
  • Perlman JH, Colson AO, Wang W, Bence K, Osman R, Gershengorn MC: Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotrophin-releasing hormone receptor. J Biol Chem 1997 May; 272(18):11937-42,
  • Chu W, Perlman JH, Gershengorn MC, Moeller KD: Thyrotrophin-releasing hormone analogs: a building block approach to the construction of tetracyclic peptidomimetics. Bioorg Med Chem Lett 1998 Nov 3; 8(21):3093-6,
  • Rutledge LD, Perlman JH, Gershengorn MC, Marshall GR, Moeller KD: Conformationally restricted TRH analogs: a probe for the pyroglutamate region. J Med Chem 1996 Apr 12; 39(8):1571-4,
  • Perlman JH, Laakkonen L, Osman R, Gershengorn MC: A model of the thyrotrophin-releasing hormone (TRH) receptor binding pocket. Evidence for a second direct interaction between transmembrane helix 3 and TRH. J Biol Chem 1994 Sep 23; 269(38):23383-6.,
  • Colson AO, Perlman JH, Smolyar A, Gershengorn MC, Osman R: Static and dynamic roles of extracellular loops in G protein-coupled receptors: a mechanism for sequential binding of thyrotrophin-releasing hormone to its receptor. Biophys J 1998 Mar; 74(3):1087-1100,
  • Colson AO, Perlman JH, Jinsi-Parimoo A, Nussenzveig DR, Osman R, Gershengorn MC: A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotrophin-releasing hormone receptor in an inactive conformation. Mol Pharmacol 1998 Dec; 54(6):968-78,
  • Laakkonen L, Li W, Perlman JH, Guarnieri F, Osman R, Moeller KD, Gershengorn MC: Restricted analogs provide evidence of a biologically active conformation of thyrotrophin-releasing hormone. Mol Pharmacol 1996 Jun; 49(6):1092-6,
  • Perlman JH, Laakkonen LJ, Guarnieri F, Osman R, Gershengorn MC: A refined model of the thyrotrophin-releasing hormone (TRH) receptor binding pocket. Experimental analysis and energy minimization of the complex between TRH and TRH receptor. Biochemistry 1996 Jun 18; 35(24):7643-50,
  • Perlman JH, Nussenzveig DR, Osman R, Gershengorn MC: Thyrotrophin-releasing hormone binding to the mouse pituitary receptor does not involve ionic interactions. A model for neutral peptide binding to G protein-coupled receptors. J Biol Chem 1992 Dec 5; 267(34):24413-7,
  • Perlman JH, Laakkonen L, Thaw CN, Osman R, Gershengorn MC: Analysis of the role of transmembrane helix three of the thyrotrophin-releasing hormone (TRH) receptor in directly binding TRH. Trans Assoc Am Physicians 1993; 106:162-7.,
  • Perlman JH, Laakkonen L, Osman R, Gershengorn MC: Distinct roles for arginines in transmembrane helices 6 and 7 of the thyrotrophin-releasing hormone receptor. Mol Pharmacol 1995 Mar; 47(3):480-4,
  • Jain R, Singh J, Perlman JH, Gershengorn MC: Synthesis and biology of new TRH analogues. Bioorg Med Chem 2002 Jan; 10(1):189-94,
  • Perlman JH, Wang W, Nussenzveig DR, Gershengorn MC: A disulfide bond between conserved extracellular cysteines in the thyrotrophin-releasing hormone receptor is critical for binding. J Biol Chem 1995 Oct 20; 270(42):24682-5,
  • Bucci E, Fronticelli C, Flanigan K, Perlman J, Steiner RF: Fluorescence anisotropy decay studies upon hemoglobin A and its subunits. Biopolymers 1979 May; 18(5):1261-76.,

Languages Spoken

  • English

Memberships & Professional Affiliations

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