Dr. Roohi however refused to test my son for a genetic variant he has a fifty percent chance of having, because it is of unknown significance. When I tried to explain my history and explain, she informed me she spent time at Harvard, and flat out refused to have my son tested. The variant does alter the size and PH level of the protein. Prior (better) geneticists treated me as if I had this disease and, I improved dramatically. Then at Mayo clinic I was diagnosed with said disease.