NoHist DM Chlorpheniramine Maleate, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride

Get an overview of NOHIST DM (chlorpheniramine maleate, dextromethorphan hydrobromide and phenylephrine hydrochloride liquid), including its generic name, formulation (i.e. pill, oral solution, injection, inhaled medicine) and why it’s used. The medication in NoHist DM can be sold under different names.

Refer to the “Also Known As” section to reference different products that include the same medication as NoHist DM.

Drug Basics

Brand Name: NoHist DM



Route: ORAL

Dosage Form: LIQUID

Data Current As Of: 2019-11-18

Drug Facts

active ingredients

(In each 5 mL teaspoonful)

Chlorpheniramine Maleate, USP 4 mg

Dextromethorphan HBr, USP 15 mg

Phenylephrine HCl, USP 10 mg


Chlorpheniramine Maleate Antihistamine

Dextromethorphan HBr Antitussive (cough suppressant)

Phenylephrine HCl Nasal decongestant


temporarily relieves these symptoms due to hay fever (allergic rhinitis):

  • cough due to minor throat and bronchial irritation
  • runny nose
  • sneezing
  • itchy, watery eyes
  • itching of the nose or throat
  • temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies
  • temporarily restores freer breathing through the nose


Do not use

  • to sedate a child or make a child sleepy
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for two weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this drug.

ask a doctor before use if you have

ask a doctor or pharmacist before use if you are

  • taking any other nasal decongestant or stimulant
  • taking sedatives or tranquilizers

when using this product

Do not exceed recommended dosage.

  • marked drowsiness may occur
  • avoid alcoholic beverages
  • alcohol, sedatives, and tranquilizers may increase drowsiness
  • be careful when driving a motor vehicle or operating machinery
  • excitability may occur, especially in children

stop use & ask a doctor if

  • nervousness, dizziness, or sleeplessness occur.
  • cough or nasal congestion persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache. These could be signs of a serious condition.

if pregnant or breast-feeding

ask a health professional before use.

keep out of the reach of children

In case of overdose, get medical help or contact a Poison Control Center immediately.


Do not exceed 6 doses in a 24-hour period

Age Dose
Adults and children over 12 years of age 1 teaspoonsful (5 mL) every 4 hours
Children 6 to under 12 years of age 1/2 teaspoonsful (2.5 mL) every 4 hours
Children under 6 years of age Ask your doctor

other information

  • store at 20°-25°C (68°-77°F)
  • very low sodium, contains 5 mg sodium per 5 mL teaspoonful

inactive ingredients

citric acid, edetate disodium, glycerin, grape flavoring, methylparaben, propylene glycol, propylparaben, purified water, saccharin sodium, and sodium citrate dihydrate

questions or comments

Call 1-601-855-7678 weekdays from 9:00 am to 4:00 pm CST or go to

This drug label information is as submitted to the Food and Drug Administration (FDA) and is intended for informational purposes only. If you think you may have a medical emergency, immediately call your doctor or dial 911. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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