Myrbetriq's Dosage: What to Know

Medically Reviewed By Alex Brewer, PharmD, MBA

Myrbetriq: Introduction

Myrbetriq is a brand-name prescription medication that contains the active drug mirabegron. It belongs to a class of drugs called beta-3 adrenergic agonists. A generic form of Myrbetriq has been approved, but a date of availability hasn’t been confirmed.

This medication has been approved by the Food and Drug Administration (FDA) to treat:

  • overactive bladder (OAB) in adults with specific symptoms, used alone or in combination with solifenacin
  • neurogenic detrusor overactivity (NDO) in children ages 3 years and older

In this article, you’ll find information about Myrbetriq’s dosage and details on how to take the drug. For a comprehensive overview of Myrbetriq and symptoms of OAB and NDO, view this article.

Finding a healthcare professional

If you’re interested in taking Myrbetriq, search here to find a doctor who might prescribe it.

This article describes typical recommended dosages for Myrbetriq. These dosages are provided by the drug’s manufacturer.

Your doctor will prescribe the dosage of Myrbetriq that’s best for you.

Myrbetriq: Dosage

This section presents commonly recommended dosages for Myrbetriq.

You should take the dosage your doctor prescribes for you. They’ll recommend the dosage that’s best for your condition or your child’s condition.

Myrbetriq’s forms and strengths

Myrbetriq comes in the following forms and strengths.

  • Tablet: 25 milligrams (mg), 50 mg
  • Granules:* 8 mg per milliliter (mL)

Both forms are to be swallowed.

* Your pharmacist will prepare a liquid suspension of Myrbetriq from the granules when dispensing it to you. Myrbetriq granules are not approved for use in adults.

Typical recommended dosages

Usually, doctors will prescribe a low dosage of Myrbetriq at the start of treatment. Then, they’ll adjust the dosage over time if needed. Ultimately, the doctor will prescribe the smallest dosage of Myrbetriq that gives the desired effect.

Adult’s dosage of Myrbetriq tablets for overactive bladder

The recommended dosage for overactive bladder is the same whether you’re taking Myrbetriq tablets* alone or in combination with solifenacin. Your doctor will prescribe the dosage of Myrbetriq that’s right for your condition.

  • Starting dosage: 25 mg taken once daily
  • Maintenance dosage: 25 mg to 50 mg taken once daily
  • Maximum dosage: 50 mg taken once daily

* Myrbetriq granules are not approved for use in adults.

Children’s dosage of Myrbetriq granules for neurogenic detrusor overactivity

The table below shows recommended dosages of Myrbetriq granules for neurogenic detrusor overactivity (NDO) in children ages 3 years and older. The dosage of Myrbetriq granules is based on weight. For reference, 1 kilogram (kg) is about 2.2 pounds (lb).

Body weight in kg Approximate body weight in lb Starting dosage Maintenance dosage Maximum dosage
11 kg to less than 22 kg 24 lb to less than 48 lb 24 mg taken once daily 24 mg to 48 mg taken once daily 48 mg taken once daily
22 kg to less than 35 kg 48 lb to less than 77 lb 32 mg taken once daily 32 mg to 64 mg taken once daily 64 mg taken once daily
35 kg or greater 77 lb or greater 48 mg taken once daily 48 mg to 80 mg taken once daily 80 mg taken once daily

For example, assume a doctor prescribes Myrbetriq granules for a child weighing 25 kg (about 55 lb). The child’s starting dosage will be 32 mg taken once daily. If needed, the doctor may increase the child’s dosage up to a maximum of 64 mg taken once daily.

Children’s dosage of Myrbetriq tablets for NDO

Children ages 3 years and older weighing at least 35 kg (about 77 lb) may take Myrbetriq tablets for NDO. The recommended dosages are as follows:

  • Starting dosage: 25 mg once daily
  • Maintenance dosage: 25 mg to 50 mg once daily
  • Maximum dosage: 50 mg once daily

Length of treatment

Doctors typically prescribe Myrbetriq as a long-term treatment. You and the doctor will discuss whether it’s safe and effective for the condition it’s treating. If you agree it is, you or your child likely will take it long term.

Myrbetriq: Common questions about dosage

The following common questions relate to Myrbetriq’s dosage.

Should I take my Myrbetriq dose at a certain time of day?

You may take your Myrbetriq dose at any time. However, try to take it at the same time each day. This helps to keep a steady amount of medication in your body. It also may make it easier to remember to take it regularly.

Ask your doctor or pharmacist if you have any questions about taking your dose.

Do doctors prescribe Myrbetriq in 100-mg doses?

No, the maximum recommended dosage of Myrbetriq for use in adults is 50 milligrams (mg) taken once daily.

The maximum recommended dosage of Myrbetriq for use in children varies by the form and other factors. See the children’s dosage information in the “Myrbetriq: Dosage” section above to learn more.

Always take the dosage of Myrbetriq that your doctor prescribes.

Is Myrbetriq considered safe? Are there certain doses of the drug that aren’t safe?

A drug must be safe and effective to be approved by the Food and Drug Administration (FDA). The process to find recommended dosages takes years of clinical studies and testing.

That said, it could be unsafe to take a dose that’s higher than your doctor prescribes.

For information about side effects and Myrbetriq, see this article. Talk with your doctor or pharmacist if you have questions about Myrbetriq’s dosage and safety.

Is Myrbetriq a diuretic? If not, is its dosage similar to that of a diuretic?

No, Myrbetriq is not a diuretic. Diuretic medications increase the amount of water and sodium (salt) that passes through the kidneys. In turn, this may help increase frequency of urination and urine volume.

On the other hand, Myrbetriq relaxes the bladder so it can hold more urine. This helps decrease urinary urgency and frequency.

Diuretics may be taken once daily or more often. Their recommended dosage varies by medication. Conversely, Myrbetriq is taken once daily, and its dosage varies by condition and sometimes weight.

Talk with your doctor or pharmacist if you have additional questions about diuretics or Myrbetriq.

Myrbetriq: Missing a dose

If you miss a dose of Myrbetriq, take it as soon as you remember. However, if it’s been more than 12 hours since your last dose, skip the missed dose. Take your next dose at the usual time.

View these medication reminder options to help avoid missing doses. You could also set an alarm or download a reminder app on your phone.

Myrbetriq: Dosage considerations

Doctors will consider several factors when prescribing the dosage for Myrbetriq. These factors include:

  • your age (or your child’s age, if Myrbetriq is being used for a child)
  • the condition Myrbetriq will be used to treat
  • the severity of your condition (or your child’s condition, if Myrbetriq is being used for a child)
  • the form of Myrbetriq

The dosage prescribed also may vary based on whether the person taking Myrbetriq has any other medical conditions.

Recommended adjustments in dosage

If you have certain liver or kidney problems, your doctor may adjust your Myrbetriq dosage. This is also true for children taking Myrbetriq.

Myrbetriq: How to take

Myrbetriq comes as tablets. It also comes as granules that are prepared to make a liquid suspension. Your pharmacist will prepare the suspension of Myrbetriq when dispensing it to you.

You’ll take either form once daily. Specific information for taking either form is as follows.

  • Myrbetriq tablets
    • Do not break, crush, or chew the tablets.
    • Swallow the tablets whole with a glass of water.
    • Adults can take Myrbetriq with or without food.
    • Children should take Myrbetriq with food.
  • Myrbetriq granules
    • Shake the bottle well for 1 minute.
    • Let the bottle stand until the foam is gone (about 1 minute to 2 minutes).
    • Place the dose in the oral dosing device, which comes with Myrbetriq.
    • Take the dose within 1 hour with food.
    • Wash the oral dosing device with mild dish detergent. Then rinse it and let it dry.

If your doctor prescribes solifenacin in combination with Myrbetriq, take both medications at the same time.

If you or your child has difficulty swallowing tablets, view this article. It provides suggestions on how to take this form of medication. You also can talk with your doctor or pharmacist about taking the medication.

ACCESSIBLE DRUG LABELS AND CONTAINERS

If you find it challenging to read the label on your prescription, tell your doctor or pharmacist. Certain pharmacies provide medication labels with large print or braille. They may also offer labels containing a scannable code that your smartphone can convert from text to speech. If your pharmacy doesn’t provide these choices, your doctor or pharmacist may be able to recommend a pharmacy that does.

If it’s difficult for you to open medication bottles, ask your pharmacist if they can dispense Myrbetriq in an easy-open container. They also may recommend ways to help make it easier to open the bottles.

Myrbetriq: Overdose

If you or your child takes more than the recommended dosage of Myrbetriq, serious effects can occur. Do not take more Myrbetriq than the doctor prescribes. 

Symptoms of overdose

Symptoms that an overdose of Myrbetriq could cause include:

  • heart palpitations
  • increased pulse
  • increased blood pressure

What to do in case of overdose

Call your doctor if you think you’ve taken too much of this drug. Also, you can call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. However, if your symptoms are severe, call 911 or a local emergency number. Or go to the nearest emergency room right away.

Myrbetriq: What to discuss with your doctor

Talk with the doctor or pharmacist for additional information about Myrbetriq’s dosage. Keep in mind that the dosages presented in this article are typical dosages from the drug’s manufacturer. Your doctor will recommend the dosage of Myrbetriq that’s right for you and your condition. Always follow the dosage that your doctor prescribes for you.

As with any medications you’re taking, do not change your Myrbetriq dosage without a recommendation from your doctor.

In addition to discussing Myrbetriq with your doctor, you may find the following articles helpful in learning more.

  • Overview of Myrbetriq. For comprehensive details on Myrbetriq, see this article.
  • Drug comparisons. To learn how Myrbetriq compares with similar drugs, read this article.
  • Information on side effects. If you’d like to know about possible side effects of Myrbetriq, view this article.
  • Cost and savings options. For information about Myrbetriq’s cost and ways to save on your prescription, read this article.
  • Details about interactions. If you want to find out about possible interactions with Myrbetriq, view this article.
  • Details about Myrbetriq’s indications. To learn more about the conditions Myrbetriq is used to treat, see these articles:

Disclaimer: Healthgrades has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.


Medical Reviewer: Alex Brewer, PharmD, MBA
Last Review Date: 2022 Dec 9
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