Lynparza’s Dosage: What to Know

Medically Reviewed By Amber R. Watson, PharmD

Lynparza: Introduction

Lynparza is a brand-name prescription medication that contains the active drug olaparib. It belongs to a class of drugs called poly ADP-ribose polymerase (PARP) inhibitors. Lynparza is not available in a generic form.

This medication has been approved by the Food and Drug Administration (FDA) for use in adults to treat certain types of:

Doctors often prescribe Lynparza for cancers with specific changes in certain genes. This includes BRCA-positive cancers.

In this article, you’ll find additional information about Lynparza’s dosage and details on how to take the drug. For a comprehensive overview of Lynparza, view this article.

Finding a healthcare professional

If you’re interested in taking Lynparza, search here to find a doctor who might prescribe it.

This article describes typical recommended dosages for Lynparza. These dosages are provided by the drug’s manufacturer.

Always follow the dosage of Lynparza that your doctor prescribes.

Lynparza: Dosage

Commonly recommended dosages for Lynparza are shown below. However, your doctor will prescribe the Lynparza dosage that’s right for you.

Lynparza’s form and strengths

Lynparza is available as an oral tablet. It comes in the following strengths:

  • 100 milligrams (mg)
  • 150 mg

Typical recommended dosages

The table below describes the recommended dosages for Lynparza’s approved uses.

Condition Dose Frequency
breast cancer 300 mg twice per day
ovarian cancer 300 mg twice per day
pancreatic cancer 300 mg twice per day
prostate cancer 300 mg twice per day

Length of treatment

Doctors typically prescribe Lynparza as a long-term treatment. You’ll likely take it long term if you and your doctor feel it’s safe and effective for your condition.

Lynparza: Common questions about dosage

Below are some common questions related to Lynparza’s dosage.

Would my doctor ever reduce my Lynparza dosage?

Yes, your doctor may need to reduce your dosage of Lynparza in some situations. These include:

  • developing side effects from taking Lynparza
  • having kidney problems
  • taking certain medications

See the “Lynparza: Dosage” section above for the recommended dosages.

To learn more about adjusting the dosage of Lynparza, talk with your doctor or pharmacist.

Is there a Lynparza 50-mg or 150-mg daily dosage?

No, there’s no 50-milligram (mg) or 150-mg daily dose of Lynparza. The recommended dosage for Lynparza’s approved uses is 300 mg twice per day. However, your doctor may lower your dosage to 150 mg twice per day if you take certain medications.

Lynparza used to be available as a 50-mg capsule. The usual daily dosage was eight capsules (400 mg) twice per day. The manufacturer replaced the capsules with tablets and stopped making the capsules in 2018.

If you have questions about the daily dose of Lynparza, ask your doctor or pharmacist.

Lynparza: Dosage considerations

Your doctor will consider several factors when prescribing the dosage for Lynparza. These factors include:

  • any side effects you’re experiencing
  • other medications you take
  • your kidney function

Recommended adjustments in dosage

Your doctor may lower your dosage of Lynparza if you take certain medications or have kidney problems.

Your doctor may also lower your dosage if you develop side effects from the drug. If you’d like to know about possible side effects of Lynparza, view this article.

Lynparza: How to take

Lynparza comes as an oral tablet. You’ll take it by mouth. You need to swallow the tablet whole. Do not chew, crush, dissolve, or split the tablet in half.

You can take Lynparza with or without food. However, you should avoid grapefruit, Seville (bitter) oranges, and juice from either fruit during treatment with Lynparza. These foods can interact with the drug.

You should take Lynparza doses 12 hours apart. Take each dose around the same time of day. Doing so will help maintain a consistent amount of the drug in your body. And this can help Lynparza work effectively.

If you have difficulty swallowing tablets, view this article. It provides suggestions on how to take this form of medication. Also, talk with your doctor or pharmacist about taking your medication.


If you find it challenging to read the label on your prescription, tell your doctor or pharmacist. Certain pharmacies provide medication labels with large print or braille. They may also offer labels containing a scannable code that your smartphone can convert from text to speech. If your pharmacy doesn’t provide these choices, your doctor or pharmacist may be able to recommend a pharmacy that does.

If it’s difficult for you to open medication bottles, ask your pharmacist if they can dispense Lynparza in an easy-open container. They also may recommend ways to help make it easier to open the bottles.

Lynparza: Missing a dose

If you miss a dose of Lynparza, skip the missed dose. Take your next dose at the regularly scheduled time.

View these medication reminder options to help avoid missing doses. You could also set an alarm or download a reminder app on your phone.

Lynparza: Overdose

For some drugs, taking more than the recommended dosage may lead to unwanted side effects or overdose. Do not take more Lynparza than your doctor prescribes.

What to do if you take too much Lynparza

Call your doctor if you think you’ve taken too much of this drug. Also, you can call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. However, if your symptoms are severe, call 911 or a local emergency number. Or go to the nearest emergency room right away.

Lynparza: What to discuss with your doctor

Talk with your doctor or pharmacist for additional information about Lynparza’s dosage. Keep in mind that the dosages presented in this article are typical dosages provided by the drug’s manufacturer. Your doctor will recommend the dosage of Lynparza that’s right for you and your condition. Always follow the dosage that your doctor prescribes for you.

As with any medications you’re taking, do not change your Lynparza dosage without a recommendation from your doctor.

In addition to discussing Lynparza with your doctor, you may find the following articles helpful in learning more.

Disclaimer: Healthgrades has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Medical Reviewer: Amber R. Watson, PharmD
Last Review Date: 2022 Dec 2
View All Drugs Articles
THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Never ignore professional medical advice in seeking treatment because of something you have read on the site. If you think you may have a medical emergency, immediately call your doctor or dial 911.