Gengraf Cyclosporine

Get an overview of GENGRAF (cyclosporine solution), including its generic name, formulation (i.e. pill, oral solution, injection, inhaled medicine) and why it’s used. The medication in Gengraf can be sold under different names.

Refer to the “Also Known As” section to reference different products that include the same medication as Gengraf.

Drug Basics

Brand Name: Gengraf

Generic Name: CYCLOSPORINE

Drug Type: HUMAN PRESCRIPTION DRUG

Route: ORAL

Dosage Form: SOLUTION

Data Current As Of: 2019-02-11

indications & usage

kidney, liver, & heart transplantation

Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]) is indicated for the prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants. Cyclosporine (MODIFIED) has been used in combination with azathioprine and corticosteroids.

rheumatoid arthritis

Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]) is indicated for the treatment of patients with severe active, rheumatoid arthritis where the disease has not adequately responded to methotrexate. Gengraf® can be used in combination with methotrexate in rheumatoid arthritis patients who do not respond adequately to methotrexate alone.

psoriasis

Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]) is indicated for the treatment of adult, nonimmunocompromised patients with severe (i.e., extensive and/or disabling), recalcitrant, plaque psoriasis who have failed to respond to at least one systemic therapy (e.g., PUVA, retinoids, or methotrexate) or in patients for whom other systemic therapies are contraindicated, or cannot be tolerated.

While rebound rarely occurs, most patients will experience relapse with Gengraf® as with other therapies upon cessation of treatment.

contraindications

general

Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]) is contraindicated in patients with a hypersensitivity to cyclosporine or to any of the ingredients of the formulation.

rheumatoid arthritis

Rheumatoid arthritis patients with abnormal renal function, uncontrolled hypertension, or malignancies should not receive Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]).

psoriasis

Psoriasis patients who are treated with Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]) should not receive concomitant PUVA or UVB therapy, methotrexate or other immunosuppressive agents, coal tar or radiation therapy. Psoriasis patients with abnormal renal function, uncontrolled hypertension, or malignancies should not receive Gengraf®.

NDC 0074–7269–50

GENGRAF® Oral Solution (cyclosporine oral solution, USP [MODIFIED])

100 mg/mL 50 mL

WARNING: Gengraf®Oral Solution (cyclosporine oral solution, USP [MODIFIED]) is NOT BIOEQUIVALENT to Sandimmune®Oral Solution (cyclosporine oral solution, USP). Do NOT use interchangeably without a physician’s supervision.

abbvie

Rx only

label gengraf oral solution 100mg ml 50ml.jpg


NDC 0074-7269-50

50 mL

GENGRAF® Oral Solution (cyclosporine oral solution, USP [MODIFIED])

100 mg/mL

WARNING: Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]) is NOT BIOEQUIVALENT to Sandimmune® Oral Solution (cyclosporine oral solution, USP). Do NOT use interchangeably without a physician’s supervision.

Each mL contains:

cyclosporine, USP....................100 mg

abbvie

Rx only

carton gengraf oral solution 100mg ml 50ml.jpg

also known as

This drug label information is as submitted to the Food and Drug Administration (FDA) and is intended for informational purposes only. If you think you may have a medical emergency, immediately call your doctor or dial 911. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Search Drugs and Medication

Or Browse by Name

Top Reads

Love the Doctor Who Prescribed This Medication?

Top Drugs
  • Digestive health drugs manage diseases, disorders and conditions of the gastrointesinal system. They provide treatment and symptom relief for functional and structural problems with digestive organs.
  • Antibiotic, antifungal and antiviral drugs treat infectious diseases. They kill or stop the growth of microorganisms, including bacteria, fungi and viruses.
  • Birth control medications are a form of contraception. They contain either a combination of estrogen and progestin or progestin alone. There are several forms of these hormones, but most combination products contain estrogen, ethinyl estradiol, and a progestin. They work by preventing ovulation and inhibiting fertilization and implantation.
  • Mental health drugs treat conditions that affect emotional, psychological and social well-being. Doctors frequently use mental health drugs in combination with various forms of therapy to help people manage these conditions.