Doxy 100 Doxycycline
Refer to the “Also Known As” section to reference different products that include the same medication as Doxy 100.
Brand Name: Doxy 100
Generic Name: DOXYCYCLINE
Drug Type: HUMAN PRESCRIPTION DRUG
Dosage Form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Data Current As Of: 2020-03-02
indications & usage
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Doxy-cycline for Injection, USP and other antibacterial drugs, Dooxycycline for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Doxycycline for Injection, USP is indicated in infections caused by the following microorganisms:
- Rickettsiae (Rocky Mountain spotted fever, typhus fever, and the typhus group, Q fever, rickettsial pox and tick fevers).
- Mycoplasma pneumoniae (PPLO, Eaton Agent).
- Agents of psittacosis and ornithosis.
- Agents of lymphogranuloma venereum and granuloma inguinale.
- The spirochetal agent of relapsing fever (Borelia recurrentis).
The following gram-negative microorganisms:
- Haemophilus ducreyi (chancroid).
- Pasteurella pestis and Pasteurella tularensis.
- Bartonella bacilliformis.
- Bacteroides species
- Vibrio comma and Vibrio fetus.
- Brucella species (in conjunction with streptomycin).
Because many strains of the following groups of microorganisms have been shown to be resistant to tetracyclines, culture and susceptibility testing are recommended. Doxycycline is indicated for treatment of infections caused by the following gram-negative microorganisms when bacteriologic testing indicates appropriate susceptibility to the drug:
- Escherichia coli.
- Enterobacter aerogenes (formerly Aerobacter aerogenes).
- Shigella species.
- Mima species and Herellea species.
- Haemophilus influenzae (respiratory infections).
- Klebsiella species (respiratory and urinary infections).
Doxycycline is indicated for treatment of infections caused by the following gram-positive microorganisms when bacteriologic testing indicates appropriate susceptibility to the drug:
- Anthrax due to Bacillus anthracis, including inhalational anthrax (post-exposure): to reduce the incidence or progression of disease following exposure to aerosolized Bacillus anthracis.
- Streptococcus species:
Up to 44% of strains of Streptococcus pyogenes and 74% of Streptococcus pyogenes and 74% of Streptococcus faecalis have been found to be resistant to tetracycline drugs. Therefore, tetracyclines should not be used for streptococcal disease unless the organism has been demonstrated to be sensitive.
For upper respiratory infections due to group A beta-hemolytic streptococci, penicillin is the usual drug of choice, including prophylaxis of rheumatic fever.
- Diplococcus pneumoniae.
- Staphylococcus aureus, respiratory, skin and soft tissue infections. Tetracyclines are not the drugs of choice in the treatment of any type of staphylococcal infections.
When penicillin is contraindicated, doxycycline is and alternative drug in the treatment of infections due to:
- Neisseria gonorrhoeae and N. meningitidis.
- Treponema pallidum and Treponema pertenue (syphilis and yaws).
- Listeria monocytogenes.
- Clostridium species.
- Fusobacterium fusiforme (Vincent's infection).
- Actinomyces species.
In acute intestinal amebiasis, doxycycline may be a useful adjunct to amebicides. Doxycycline is indicated in the treatment of trachoma, although the infectious agent is not always eliminated, as judged by immunofluorescence.
This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines.
Anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. Hepatotoxicity has been reported rarely. These reactions have been caused by both the oral and parenteral administration of tetracyclines.
Maculopapular and erythematous rashes. Exfoliative dermatitis has been reported but is uncommon. Photosensitivity is discussed above (see WARNINGS)
Rise in BUN has been reported and is apparently dose related (see WARNINGS)
Bulging fontanels in infants and benign intracranial hypertension in adults have been reported in individuals receiving full therapeutic dosages. These conditions disappeared rapidly when the drug was discontinued.
When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of thyroid glands. No abnormalities of thyroid function studies are known to occur.
also known as
- Acticlate (tablet, coated)
- Acticlate CAP (capsule)
- Alodox (tablet)
- Doryx (tablet, delayed release)
- DOXY 100(TM) DOXYCYCLINE (injection, powder, lyophilized, for solution)
- Doxycyclate Hyclate (capsule)
- Doxycycline (injection, powder, lyophilized, for solution)
- Doxycycline (capsule)
- Doxycycline (tablet, coated)
- doxycycline hyclate (tablet, coated)
- Doxycycline Hyclate (tablet, delayed release)
- doxycycline hyclate (capsule)
- Doxycycline Hyclate (tablet, film coated)
- Doxycycline Hyclate Delayed release (tablet, delayed release)
- LymePak (tablet, film coated)
- Ocudox (capsule)
- TARGADOX (tablet)