Healthgrades Drug & Medication Database

Drugs & Medications A-Z

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The Top 50 Drugs Prescribed in the United States

Get a list of the top 50 prescription drugs out of the annual 3 billion prescriptions filled at U.S. pharmacies.
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Top Drugs

Advair

Advil

Albuterol

Allegra

Ambien

Amlodipine

Amoxicilin

Atenolol

Ativan

Atorvastatin

Augmentin

Ciproflaxin

Citalopram

Coreg

Crestor

Dyrenium

Flexeril

Flonase

Fosamax

Furosemide

Gabapentin

Keflex

Lexapro

Lisinopril

Lopressor

Lovastatin

Metformin

Mobic

Nexium

Paxil

Percocet

Plavix

Pravachol

Prednisone

Prilosec

Prozac

Septra

Singulair

Synthroid

Trazodone

Vicodin

Warfarin

Xanax

Zithromax

Zocor

Zoloft

Browse Drugs by Condition

ADHD

Asthma

Breast Cancer

Cholesterol

COPD

Crohn's Disease

Depression

Heart Failure

Hidradenitis Suppurativa

High Blood Pressure

HIV

Migraine

Multiple Sclerosis

Psoriatic Arthritis

Rheumatoid Arthritis

Type 2 Diabetes (Injectables)

Type 2 Diabetes (Oral)

Browse Top Drugs by Category

Allergies & Respiratory

Arthritis and Pain

Birth Control

Cardiology

Diabetes

Digestive Health

Infections

Mental Health

Neurology

Browse Most Common Active Ingredients

ACETAMINOPHEN (60)

ASPIRIN (56)

BENZOYL PEROXIDE (89)

BISMUTH SUBSALICYLATE (85)

CALCIUM CARBONATE (118)

CETIRIZINE HYDROCHLORIDE (106)

CLOTRIMAZOLE (43)

DEXTROMETHORPHAN HYDROBROMIDE (60)

DIMETHICONE (113)

DIPHENHYDRAMINE HYDROCHLORIDE (220)

FAMOTIDINE (42)

FEXOFENADINE HYDROCHLORIDE (48)

GUAIFENESIN (75)

IBUPROFEN (129)

LOPERAMIDE HYDROCHLORIDE (58)

LORATADINE (54)

MENTHOL (98)

MICONAZOLE NITRATE (58)

NAPROXEN SODIUM (58)

NICOTINE (75)

OXYMETAZOLINE HYDROCHLORIDE (74)

PETROLATUM (50)

PHENYLEPHRINE HYDROCHLORIDE (72)

PSEUDOEPHEDRINE HYDROCHLORIDE (44)

PYRITHIONE ZINC (76)

RANITIDINE HYDROCHLORIDE (42)

SALICYLIC ACID (314)

SODIUM FLUORIDE (68)

TOLNAFTATE (68)

ZINC OXIDE (61)

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