Healthgrades Editorial Staff

What is gout?

Gout is a common form of arthritis caused by a buildup of uric acid crystals in the joints. Uric acid is a substance in the blood that is produced by the breakdown of waste products called purines. If excessive uric acid is produced by the body or if uric acid is not eliminated effectively by the kidneys, it can form deposits of crystals in the joints.

Uric acid crystals can cause intense and sudden inflammation, pain, redness, stiffness and burning in and around joints that can persist for several weeks. Gout often starts in one of the big toes, but it can also affect the fingers, wrists, elbows, knees, ankles, heels, and other joint areas.